Epimutations in Prader-Willi and angelman syndromes

Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are neurogenetic disorders that are caused by the loss of function of imprinted genes in 15q11-q13. In a small group of patients, the disease is due to aberrant imprinting and gene silencing. Here, we describe the molecular analysis of 51 patien...

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Bibliographic Details
Main Author: El Maarri, Osman (author)
Other Authors: Buiting, Karin (author), Grob, Stephanie (author), Lich, Stephanie (author), Gillessen-Kaesbach, Gabriele (author), Horsthemke, Bernhard (author)
Format: article
Published: 2003
Online Access:http://hdl.handle.net/10725/6169
https://doi.org/10.1086/367926
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.sciencedirect.com/science/article/pii/S0002929707605734
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