Interactions between antiparkinsonian drugs and ABCB1/P-glycoprotein at the blood–brain barrier in a rat brain endothelial cell model

Parkinson's disease is a neurodegenerative disorder that requires treatment by dopaminergic agonists, which may be responsible for central side effects. We hypothesized that the efflux transporter ABCB1/P-glycoprotein played a role in brain disposition of antiparkinsonian drugs and could contro...

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Bibliographic Details
Main Author: Vautier, Sarah (author)
Other Authors: Milane, Aline (author), Fernandez, Christine (author), Buyse, Marion (author), Chacun, Helene (author), Farinotti, Robert (author)
Format: article
Published: 2008
Online Access:http://hdl.handle.net/10725/4499
http://dx.doi.org/10.1016/j.neulet.2008.06.055
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.sciencedirect.com/science/article/pii/S0304394008008793
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