Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat.
Background: High fruit intake is known to be associated with reduced riskof coronary heart disease. Our objective was to determine the effects of acute and chronic juice [grapefruit,orange, and pineapple] intake on plasma lipid profile and lipoprotein metabolism in normolipidemic rats.Material/Metho...
محفوظ في:
| المؤلف الرئيسي: | |
|---|---|
| مؤلفون آخرون: | , |
| التنسيق: | article |
| منشور في: |
2005
|
| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/2807 http://www.medscimonit.com/download/index/idArt/438850 |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
| _version_ | 1864513459405717504 |
|---|---|
| author | Daher, Costantine F. |
| author2 | Abou-Khalil, Jamil Baroody, George |
| author2_role | author author |
| author_facet | Daher, Costantine F. Abou-Khalil, Jamil Baroody, George |
| author_role | author |
| dc.creator.none.fl_str_mv | Daher, Costantine F. Abou-Khalil, Jamil Baroody, George |
| dc.date.none.fl_str_mv | 2005 2015-12-15T10:30:07Z 2015-12-15T10:30:07Z 2015-12-15 |
| dc.identifier.none.fl_str_mv | 1234-1010 http://hdl.handle.net/10725/2807 Daher, C., Abou-Khalil, J., & Baroody, G. (2005). Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. Medical science monitor, 11(12), BR465-BR472. http://www.medscimonit.com/download/index/idArt/438850 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Medical Science Monitor |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Background: High fruit intake is known to be associated with reduced riskof coronary heart disease. Our objective was to determine the effects of acute and chronic juice [grapefruit,orange, and pineapple] intake on plasma lipid profile and lipoprotein metabolism in normolipidemic rats.Material/Methods: The effects of acute juice intake were studied after three hours of a single juice-lipidload instilled intragastrically. In the chronic study, blood samples from fasted animals were subjectedto analyses after six months of either water [control] or water-juice [1:1] intake. Results: In the acutestudy, pineapple and grapefruit significantly decreased plasma triacylglycerol [TAG], and chylomicron[CM] TAG and cholesterol concentrations concomitantly with delayed gastric emptying. Plasma cholesterollevels and very-low-density lipoprotein [VLDL] secretion and metabolism were not affected. In the chronicstudy, only grapefruit significantly decreased plasma and VLDL TAG concentrations and relative VLDL particlesize with respect to other groups. All juices significantly increased VLDL apolipoprotein B [apoB] secretion,but plasma total apoB concentrations were highest in the grapefruit group and lowest in the orange andpineapple groups. No effect on blood cholesterol levels was observed. Conclusions: The cardioprotectivebenefit of chronic juice intake in normolipidemic rat may be chiefly through mechanisms independent ofa direct effect on blood lipid profile, although orange and pineapple, but not grapefruit, relativelyimproved the metabolism and clearance of blood lipoprotein particles. As a result of delayed gastricemptying, grapefruit and pineapple juices may moderate sharp increases in postprandial plasma TAG concentrationsaccompanying peak digestion and absorption. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_90be8fd08a8e79502c021ab3a393c820 |
| identifier_str_mv | 1234-1010 Daher, C., Abou-Khalil, J., & Baroody, G. (2005). Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. Medical science monitor, 11(12), BR465-BR472. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/2807 |
| publishDate | 2005 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat.Daher, Costantine F.Abou-Khalil, JamilBaroody, GeorgeBackground: High fruit intake is known to be associated with reduced riskof coronary heart disease. Our objective was to determine the effects of acute and chronic juice [grapefruit,orange, and pineapple] intake on plasma lipid profile and lipoprotein metabolism in normolipidemic rats.Material/Methods: The effects of acute juice intake were studied after three hours of a single juice-lipidload instilled intragastrically. In the chronic study, blood samples from fasted animals were subjectedto analyses after six months of either water [control] or water-juice [1:1] intake. Results: In the acutestudy, pineapple and grapefruit significantly decreased plasma triacylglycerol [TAG], and chylomicron[CM] TAG and cholesterol concentrations concomitantly with delayed gastric emptying. Plasma cholesterollevels and very-low-density lipoprotein [VLDL] secretion and metabolism were not affected. In the chronicstudy, only grapefruit significantly decreased plasma and VLDL TAG concentrations and relative VLDL particlesize with respect to other groups. All juices significantly increased VLDL apolipoprotein B [apoB] secretion,but plasma total apoB concentrations were highest in the grapefruit group and lowest in the orange andpineapple groups. No effect on blood cholesterol levels was observed. Conclusions: The cardioprotectivebenefit of chronic juice intake in normolipidemic rat may be chiefly through mechanisms independent ofa direct effect on blood lipid profile, although orange and pineapple, but not grapefruit, relativelyimproved the metabolism and clearance of blood lipoprotein particles. As a result of delayed gastricemptying, grapefruit and pineapple juices may moderate sharp increases in postprandial plasma TAG concentrationsaccompanying peak digestion and absorption.PublishedN/A2015-12-15T10:30:07Z2015-12-15T10:30:07Z20052015-12-15Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1234-1010http://hdl.handle.net/10725/2807Daher, C., Abou-Khalil, J., & Baroody, G. (2005). Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. Medical science monitor, 11(12), BR465-BR472.http://www.medscimonit.com/download/index/idArt/438850enMedical Science Monitorinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/28072017-02-10T11:22:22Z |
| spellingShingle | Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. Daher, Costantine F. |
| status_str | publishedVersion |
| title | Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. |
| title_full | Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. |
| title_fullStr | Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. |
| title_full_unstemmed | Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. |
| title_short | Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. |
| title_sort | Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. |
| url | http://hdl.handle.net/10725/2807 http://www.medscimonit.com/download/index/idArt/438850 |