Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model
Purpose: To validate a recently described animal model of abdominal aortic aneurysm (AAA) and to assess a new macroporous polyester—covered stent for endovascular AAA exclusion. Methods: Twenty adult sheep had AAAs surgically created by replacing a segment of the infrarenal aorta with an autologous...
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| مؤلفون آخرون: | , , , |
| التنسيق: | article |
| منشور في: |
2001
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/4023 http://dx.doi.org/10.1177/152660280100800408 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://jet.sagepub.com/content/8/4/390.short |
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| _version_ | 1864513462815686656 |
|---|---|
| author | El-Khoury, Joe |
| author2 | Otal, Philippe Amin, Chauki Delisle, Marie-Bernadette Cerene, Alain |
| author2_role | author author author author |
| author_facet | El-Khoury, Joe Otal, Philippe Amin, Chauki Delisle, Marie-Bernadette Cerene, Alain |
| author_role | author |
| dc.creator.none.fl_str_mv | El-Khoury, Joe Otal, Philippe Amin, Chauki Delisle, Marie-Bernadette Cerene, Alain |
| dc.date.none.fl_str_mv | 2001 2016-06-14T06:53:12Z 2016-06-14T06:53:12Z 2016-06-14 |
| dc.identifier.none.fl_str_mv | 1526-6028 http://hdl.handle.net/10725/4023 http://dx.doi.org/10.1177/152660280100800408 Soula, P., d'Othée, B. J., Otal, P., Amin, C., El Khoury, J., Delisle, M. B., ... & Rousseau, H. (2001). Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model. Journal of Endovascular Therapy, 8(4), 390-400. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://jet.sagepub.com/content/8/4/390.short |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Journal of Endovascular Therapy |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Purpose: To validate a recently described animal model of abdominal aortic aneurysm (AAA) and to assess a new macroporous polyester—covered stent for endovascular AAA exclusion. Methods: Twenty adult sheep had AAAs surgically created by replacing a segment of the infrarenal aorta with an autologous jugular venous graft. Three months later, surviving animals underwent percutaneous implantation of macroporous polyester—covered nitinol stents; 3 animals with untreated AAAs served as controls. Follow-up surveillance included spiral computed tomography at 1 month and digital subtraction angiography at 3 and 6 months. Endografted animals were sacrificed at 1, 3, and 6 months after implantation; specimens from all animals were examined grossly and microscopically. Results: Seven (35%) animals died within 24 hours of causes related to the technique; 1 animal developed paraplegia and was sacrificed on day 1. Three (25%) animals died of spontaneous aneurysm rupture at <10 days, and 6 received the stent-graft at 3 months. The macroporous cover did not prevent continued perfusion of the sac early after stent-graft deployment, but all aneurysms were excluded on the 1-month CT. Conclusions: Spontaneous AAA rupture occurred earlier and was not as frequent as previously described for this model. Implantation of the covered stent was feasible, but aneurysm exclusion was not immediate. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_929c38e1ca8e9d94550eb55ced6bfa67 |
| identifier_str_mv | 1526-6028 Soula, P., d'Othée, B. J., Otal, P., Amin, C., El Khoury, J., Delisle, M. B., ... & Rousseau, H. (2001). Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model. Journal of Endovascular Therapy, 8(4), 390-400. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/4023 |
| publishDate | 2001 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm ModelEl-Khoury, JoeOtal, PhilippeAmin, ChaukiDelisle, Marie-BernadetteCerene, AlainPurpose: To validate a recently described animal model of abdominal aortic aneurysm (AAA) and to assess a new macroporous polyester—covered stent for endovascular AAA exclusion. Methods: Twenty adult sheep had AAAs surgically created by replacing a segment of the infrarenal aorta with an autologous jugular venous graft. Three months later, surviving animals underwent percutaneous implantation of macroporous polyester—covered nitinol stents; 3 animals with untreated AAAs served as controls. Follow-up surveillance included spiral computed tomography at 1 month and digital subtraction angiography at 3 and 6 months. Endografted animals were sacrificed at 1, 3, and 6 months after implantation; specimens from all animals were examined grossly and microscopically. Results: Seven (35%) animals died within 24 hours of causes related to the technique; 1 animal developed paraplegia and was sacrificed on day 1. Three (25%) animals died of spontaneous aneurysm rupture at <10 days, and 6 received the stent-graft at 3 months. The macroporous cover did not prevent continued perfusion of the sac early after stent-graft deployment, but all aneurysms were excluded on the 1-month CT. Conclusions: Spontaneous AAA rupture occurred earlier and was not as frequent as previously described for this model. Implantation of the covered stent was feasible, but aneurysm exclusion was not immediate.PublishedN/A2016-06-14T06:53:12Z2016-06-14T06:53:12Z20012016-06-14Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1526-6028http://hdl.handle.net/10725/4023http://dx.doi.org/10.1177/152660280100800408Soula, P., d'Othée, B. J., Otal, P., Amin, C., El Khoury, J., Delisle, M. B., ... & Rousseau, H. (2001). Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model. Journal of Endovascular Therapy, 8(4), 390-400.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://jet.sagepub.com/content/8/4/390.shortenJournal of Endovascular Therapyinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/40232021-03-19T10:00:52Z |
| spellingShingle | Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model El-Khoury, Joe |
| status_str | publishedVersion |
| title | Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model |
| title_full | Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model |
| title_fullStr | Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model |
| title_full_unstemmed | Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model |
| title_short | Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model |
| title_sort | Macroporous Polyester—Covered Stent in an Experimental Abdominal Aortic Aneurysm Model |
| url | http://hdl.handle.net/10725/4023 http://dx.doi.org/10.1177/152660280100800408 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://jet.sagepub.com/content/8/4/390.short |