Optimizing clopidogrel dose response
Purpose Response to clopidogrel varies widely with nonresponse rates ranging from 4% to 30%. A reduced function of the gene variant of the CYP2C19 has been associated with lower drug metabolite levels, and hence diminished platelet inhibition. Drugs that alter CYP2C19 activity may also mimic genetic...
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| Format: | article |
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2016
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| Online Access: | http://hdl.handle.net/10725/4442 http://dx.doi.org/10.2147/TCRM.S83293 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590670/ |
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