A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes

A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes

Compartmentation of cAMP is thought to generate the specificity of Gs-coupled receptor action in cardiac myocytes, with phosphodiesterases (PDEs) playing a major role in this process by preventing cAMP diffusion. We tested this hypothesis in adult rat ventricular myocytes by characterizing PDEs invo...

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Bibliographic Details
Main Author: Rochais, Francesca (author)
Other Authors: Abi-Gerges, Aniella (author), Homer, Kathleen (author), Lefebvre, Florence (author), Cooper, Dermot M.F. (author), Conti, Marco (author), Fischmeister, Rodolphe (author), Vandecasteele, Gregoire (author)
Format: article
Published: 2006
Online Access:http://hdl.handle.net/10725/6353
https://doi.org/10.1161/01.RES.0000218493.09370.8e
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.ahajournals.org/doi/full/10.1161/01.res.0000218493.09370.8e
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Internet

http://hdl.handle.net/10725/6353
https://doi.org/10.1161/01.RES.0000218493.09370.8e
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.ahajournals.org/doi/full/10.1161/01.res.0000218493.09370.8e

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