Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells

The peritoneal environment in endometriosis is known to have growth-promoting effects on endometrial cells. To investigate whether follicular fluid, a contributor to the peritoneal fluid, stimulates endometrial cell proliferation, we incubated endometrial stromal cells in culture with various diluti...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Zreik, Tony (author)
مؤلفون آخرون: Bahtiyar, M.O. (author), Seli, E. (author), Oral, E. (author), Arici, A. (author)
التنسيق: article
منشور في: 2001
الوصول للمادة أونلاين:http://hdl.handle.net/10725/2260
http://dx.doi.org/10.1093/humrep/13.12.3492
http://humrep.oxfordjournals.org/content/13/12/3492.short
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
_version_ 1864513457853825024
author Zreik, Tony
author2 Bahtiyar, M.O.
Seli, E.
Oral, E.
Arici, A.
author2_role author
author
author
author
author_facet Zreik, Tony
Bahtiyar, M.O.
Seli, E.
Oral, E.
Arici, A.
author_role author
dc.creator.none.fl_str_mv Zreik, Tony
Bahtiyar, M.O.
Seli, E.
Oral, E.
Arici, A.
dc.date.none.fl_str_mv 2001
2015-10-06T10:53:28Z
2015-10-06T10:53:28Z
2015-10-06
dc.identifier.none.fl_str_mv 0268-1161
http://hdl.handle.net/10725/2260
http://dx.doi.org/10.1093/humrep/13.12.3492
Bahtiyar, M. O., Seli, E., Oral, E., Senturk, L. M., Zreik, T. G., & Arici, A. (1998). Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells. Human Reproduction, 13(12), 3492-3495.
http://humrep.oxfordjournals.org/content/13/12/3492.short
dc.language.none.fl_str_mv en
dc.relation.none.fl_str_mv Human Reproduction
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description The peritoneal environment in endometriosis is known to have growth-promoting effects on endometrial cells. To investigate whether follicular fluid, a contributor to the peritoneal fluid, stimulates endometrial cell proliferation, we incubated endometrial stromal cells in culture with various dilutions of follicular fluid obtained from women with or without endometriosis undergoing oocyte retrieval for in-vitro fertilization. Cell proliferation assays were performed using follicular fluid from 28 women (without endometriosis, n = 13; with endometriosis, n = 15) in eight different endometrial stromal cell culture set-ups. Cell proliferation was assessed by a colorimetric method. Maximum cell proliferation was detected when endometrial cells were incubated with 50% dilution of follicular fluid for 48 h. Follicular fluid from women with endometriosis induced significantly higher cell proliferation than follicular fluid from women without endometriosis (P < 0.05). Our findings indicate that follicular fluid contents may contribute to the growth-promoting factors in the peritoneal fluid of women with endometriosis.
eu_rights_str_mv openAccess
format article
id LAURepo_a751be54bcf10f8779f01a98a4c22859
identifier_str_mv 0268-1161
Bahtiyar, M. O., Seli, E., Oral, E., Senturk, L. M., Zreik, T. G., & Arici, A. (1998). Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells. Human Reproduction, 13(12), 3492-3495.
language_invalid_str_mv en
network_acronym_str LAURepo
network_name_str Lebanese American University repository
oai_identifier_str oai:laur.lau.edu.lb:10725/2260
publishDate 2001
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
spelling Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cellsZreik, TonyBahtiyar, M.O.Seli, E.Oral, E.Arici, A.The peritoneal environment in endometriosis is known to have growth-promoting effects on endometrial cells. To investigate whether follicular fluid, a contributor to the peritoneal fluid, stimulates endometrial cell proliferation, we incubated endometrial stromal cells in culture with various dilutions of follicular fluid obtained from women with or without endometriosis undergoing oocyte retrieval for in-vitro fertilization. Cell proliferation assays were performed using follicular fluid from 28 women (without endometriosis, n = 13; with endometriosis, n = 15) in eight different endometrial stromal cell culture set-ups. Cell proliferation was assessed by a colorimetric method. Maximum cell proliferation was detected when endometrial cells were incubated with 50% dilution of follicular fluid for 48 h. Follicular fluid from women with endometriosis induced significantly higher cell proliferation than follicular fluid from women without endometriosis (P < 0.05). Our findings indicate that follicular fluid contents may contribute to the growth-promoting factors in the peritoneal fluid of women with endometriosis.PublishedN/A2015-10-06T10:53:28Z2015-10-06T10:53:28Z20012015-10-06Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0268-1161http://hdl.handle.net/10725/2260http://dx.doi.org/10.1093/humrep/13.12.3492Bahtiyar, M. O., Seli, E., Oral, E., Senturk, L. M., Zreik, T. G., & Arici, A. (1998). Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells. Human Reproduction, 13(12), 3492-3495.http://humrep.oxfordjournals.org/content/13/12/3492.shortenHuman Reproductioninfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/22602019-02-28T09:56:08Z
spellingShingle Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells
Zreik, Tony
status_str publishedVersion
title Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells
title_full Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells
title_fullStr Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells
title_full_unstemmed Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells
title_short Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells
title_sort Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells
url http://hdl.handle.net/10725/2260
http://dx.doi.org/10.1093/humrep/13.12.3492
http://humrep.oxfordjournals.org/content/13/12/3492.short