Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI
Objectives: To retrospectively compare the diagnostic value of MRI with integrative spectroscopy (MRI/spec), to anatomically fused FDG PET/MRI (PET/MRI) in brain lesions. Methods: Twenty-four patients (n= 27 brain lesions) underwent MRI/spec (LX 1.5T, GE; Achieva 3.0T, Philips) and standard FDG PET/...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , |
| التنسيق: | article |
| منشور في: |
2008
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/6448 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://jnm.snmjournals.org/content/49/supplement_1/223P.2.short |
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| _version_ | 1864513479821492224 |
|---|---|
| author | Nassif, Anis |
| author2 | Nguyen, Nghi Sayed, Mohamed Osman, Medhat |
| author2_role | author author author |
| author_facet | Nassif, Anis Nguyen, Nghi Sayed, Mohamed Osman, Medhat |
| author_role | author |
| dc.creator.none.fl_str_mv | Nassif, Anis Nguyen, Nghi Sayed, Mohamed Osman, Medhat |
| dc.date.none.fl_str_mv | 2008 2017-11-01T07:49:25Z 2017-11-01T07:49:25Z 2017-11-01 |
| dc.identifier.none.fl_str_mv | 0097-9058 http://hdl.handle.net/10725/6448 Nguyen, N., Nassif, A., Sayed, M., & Osman, M. (2008). Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI. Journal of Nuclear Medicine, 49(supplement 1), 223P-223P. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://jnm.snmjournals.org/content/49/supplement_1/223P.2.short |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Journal of Nuclear Medecine |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Objectives: To retrospectively compare the diagnostic value of MRI with integrative spectroscopy (MRI/spec), to anatomically fused FDG PET/MRI (PET/MRI) in brain lesions. Methods: Twenty-four patients (n= 27 brain lesions) underwent MRI/spec (LX 1.5T, GE; Achieva 3.0T, Philips) and standard FDG PET/CT including the brain (Gemini or GeminiTF, Philips) within a 3-month period. Transaxial MRI and PET images of the brain were fused using Extended Brilliance workstation (Philips). Histopathology or imaging follow-up served as reference standard. Group A (21 lesions): metastatic lesions or grade III/IV primary brain tumors; group B (6 lesions): grade I/II primary brain tumors or non-tumor lesions. PET criteria: Increased uptake in the center or periphery of the lesion was group A, otherwise group B. MRI/spec criteria: based on prior reading in reports. Results: MRI/spec and PET/MRI characterized 20/27 (74%) and 23/27 (85%) lesions correctly, and 5/27 (19%) and 4/27 (15%) lesions incorrectly. Findings of combined MRI/spec and PET/MRI are summarized in a table. Conclusions: Due to its detailed anatomical information, MRI/spec is better than PET/MRI in detecting and characterizing lesions < 2 cm. However, PET/MRI appears to characterize lesions > 2 cm better than MRI/spec because of the high specificity of FDG PET for high-grade tumors. PET/MRI can have added value in lesions that are being interpreted as indeterminate by MRI/spec. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_ab026488a91229afdf8e657231ff28ee |
| identifier_str_mv | 0097-9058 Nguyen, N., Nassif, A., Sayed, M., & Osman, M. (2008). Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI. Journal of Nuclear Medicine, 49(supplement 1), 223P-223P. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/6448 |
| publishDate | 2008 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRINassif, AnisNguyen, NghiSayed, MohamedOsman, MedhatObjectives: To retrospectively compare the diagnostic value of MRI with integrative spectroscopy (MRI/spec), to anatomically fused FDG PET/MRI (PET/MRI) in brain lesions. Methods: Twenty-four patients (n= 27 brain lesions) underwent MRI/spec (LX 1.5T, GE; Achieva 3.0T, Philips) and standard FDG PET/CT including the brain (Gemini or GeminiTF, Philips) within a 3-month period. Transaxial MRI and PET images of the brain were fused using Extended Brilliance workstation (Philips). Histopathology or imaging follow-up served as reference standard. Group A (21 lesions): metastatic lesions or grade III/IV primary brain tumors; group B (6 lesions): grade I/II primary brain tumors or non-tumor lesions. PET criteria: Increased uptake in the center or periphery of the lesion was group A, otherwise group B. MRI/spec criteria: based on prior reading in reports. Results: MRI/spec and PET/MRI characterized 20/27 (74%) and 23/27 (85%) lesions correctly, and 5/27 (19%) and 4/27 (15%) lesions incorrectly. Findings of combined MRI/spec and PET/MRI are summarized in a table. Conclusions: Due to its detailed anatomical information, MRI/spec is better than PET/MRI in detecting and characterizing lesions < 2 cm. However, PET/MRI appears to characterize lesions > 2 cm better than MRI/spec because of the high specificity of FDG PET for high-grade tumors. PET/MRI can have added value in lesions that are being interpreted as indeterminate by MRI/spec.PublishedN/A2017-11-01T07:49:25Z2017-11-01T07:49:25Z20082017-11-01Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0097-9058http://hdl.handle.net/10725/6448Nguyen, N., Nassif, A., Sayed, M., & Osman, M. (2008). Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI. Journal of Nuclear Medicine, 49(supplement 1), 223P-223P.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://jnm.snmjournals.org/content/49/supplement_1/223P.2.shortenJournal of Nuclear Medecineinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/64482021-03-19T10:03:28Z |
| spellingShingle | Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI Nassif, Anis |
| status_str | publishedVersion |
| title | Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI |
| title_full | Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI |
| title_fullStr | Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI |
| title_full_unstemmed | Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI |
| title_short | Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI |
| title_sort | Characterization of brain lesions using MRI/spectroscopy versus FDG PET fused with MRI |
| url | http://hdl.handle.net/10725/6448 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://jnm.snmjournals.org/content/49/supplement_1/223P.2.short |