Pre-Term Pre-Labor Rupture of Membranes and the Role of Amniocentesis
Pre-labour premature rupture of membranes (PPROM) is defined as rupture of membranes more than 1 hour prior to the onset of labour at <37 weeks gestation. PPROM occurs in approximately 3% of pregnancies and is responsible for a third of all preterm births. Once membranes are ruptured prolonging t...
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2010
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| Online Access: | http://hdl.handle.net/10725/3984 http://dx.doi.org/10.1017/S096553951000001X http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=7773256&fileId=S096553951000001X |
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| Summary: | Pre-labour premature rupture of membranes (PPROM) is defined as rupture of membranes more than 1 hour prior to the onset of labour at <37 weeks gestation. PPROM occurs in approximately 3% of pregnancies and is responsible for a third of all preterm births. Once membranes are ruptured prolonging the pregnancy has no maternal physical advantage but fetal morbidity and mortality are improved daily at early gestations: 19% of those infants born <25 weeks develop cerebral palsy (CP) and 28% have severe motor disability. Those infants born extremely pre term (<28 weeks) cost the public sector £75835 (95% CI £27906–145508) per live birth not to mention the emotional cost to the family. To prolong gestation is therefore the suggested goal: however how and why might we delay birth in those at risk? |
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