Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant
Background: Jump to section Background: Design and methods: Results: Conclusions: Introduction Methods Results Discussion Conclusions Transparency Several studies that evaluated achieving lipid goals have demonstrated an undertreatment of dyslipidemia. We evaluated the use and efficacy of lipid-lowe...
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| مؤلفون آخرون: | , , |
| التنسيق: | article |
| منشور في: |
2014
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/4038 http://dx.doi.org/ 10.1007/BF0012365710.1185/03007995.2014.929095 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.tandfonline.com/doi/abs/10.1185/03007995.2014.929095 |
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| _version_ | 1864513462829318144 |
|---|---|
| author | Ghanem, Georges |
| author2 | Hammoudeh, Ayman J. Echtay, Akram Haddad, Jihad |
| author2_role | author author author |
| author_facet | Ghanem, Georges Hammoudeh, Ayman J. Echtay, Akram Haddad, Jihad |
| author_role | author |
| dc.creator.none.fl_str_mv | Ghanem, Georges Hammoudeh, Ayman J. Echtay, Akram Haddad, Jihad |
| dc.date.none.fl_str_mv | 2014 2016-06-15T07:35:10Z 2016-06-15T07:35:10Z 2016-06-15 |
| dc.identifier.none.fl_str_mv | 0300-7995 http://hdl.handle.net/10725/4038 http://dx.doi.org/ 10.1007/BF0012365710.1185/03007995.2014.929095 Hammoudeh, A. J., Echtay, A., Ghanem, G. Y., & Haddad, J. (2014). Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant: the CEntralized Pan-Levant survey on tHE Undertreatment of hypercholeSterolemia (CEPHEUS) study. Current medical research and opinion, 30(10), 1957-1965. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.tandfonline.com/doi/abs/10.1185/03007995.2014.929095 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Current Medical Research and Opinion |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant the CEntralized Pan-Levant survey on tHE Undertreatment of hypercholeSterolemia (CEPHEUS) study |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Background: Jump to section Background: Design and methods: Results: Conclusions: Introduction Methods Results Discussion Conclusions Transparency Several studies that evaluated achieving lipid goals have demonstrated an undertreatment of dyslipidemia. We evaluated the use and efficacy of lipid-lowering agents (LLAs) in reducing low-density lipoprotein cholesterol (LDL-C) to recommended levels in the Levant region. Design and methods: Jump to section Background: Design and methods: Results: Conclusions: Introduction Methods Results Discussion Conclusions Transparency A multi-center, cross-sectional survey enrolled 1002 dyslipidemic patients (August 2010 – January 2011) on LLAs for ≥3 months. Collection of data and blood samples was done over one visit. Physicians and patients filled out questionnaires pertaining to dyslipidemia diagnosis and treatment. LDL-C target levels were defined according to international guidelines. Results: Jump to section Background: Design and methods: Results: Conclusions: Introduction Methods Results Discussion Conclusions Transparency The full analysis set included 992 patients. Mean age was 58.0 ± 11.6 years (41% women, 65.7% diabetics and 51.5% had history of coronary heart disease). LLAs were prescribed for primary prevention or secondary prevention or familial hypercholesterolemia in 45.8% and 52.8% and 1.4% of patients; respectively. Overall, 64.0% and 56.8% of the patients attained their LDL-C goal recommended by the NCEP ATP III and TJETF guidelines, respectively. According to the 2004 NCEP ATP III updated guidelines, about 24.8% of the very high risk group attained their LDL goal of ≤70 mg/dL. Smoking, diabetes, metabolic syndrome, history of cardiovascular disease, increased waist circumference, and elevated pre-treatment LDL-C level were all associated with not reaching LDL-C goals. Conclusions: Jump to section Background: Design and methods: Results: Conclusions: Introduction Methods Results Discussion Conclusions Transparency Although the study cohort was a relatively high risk group and might not be representative of the general population, we found that about 60% of enrolled individuals achieved the LDL-C treatment goals and 24.8% of the very high risk group achieved the recommended LDL-C targets of ≤70 mg/dl; national strategies and aggressive awareness campaigns to effectively control lipid levels to recommended target levels, especially in the high risk groups, are urgently needed. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_b393285c679b3d9f196dd60e4c638b27 |
| identifier_str_mv | 0300-7995 Hammoudeh, A. J., Echtay, A., Ghanem, G. Y., & Haddad, J. (2014). Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant: the CEntralized Pan-Levant survey on tHE Undertreatment of hypercholeSterolemia (CEPHEUS) study. Current medical research and opinion, 30(10), 1957-1965. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/4038 |
| publishDate | 2014 |
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| spelling | Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levantthe CEntralized Pan-Levant survey on tHE Undertreatment of hypercholeSterolemia (CEPHEUS) studyGhanem, GeorgesHammoudeh, Ayman J.Echtay, AkramHaddad, JihadBackground: Jump to section Background: Design and methods: Results: Conclusions: Introduction Methods Results Discussion Conclusions Transparency Several studies that evaluated achieving lipid goals have demonstrated an undertreatment of dyslipidemia. We evaluated the use and efficacy of lipid-lowering agents (LLAs) in reducing low-density lipoprotein cholesterol (LDL-C) to recommended levels in the Levant region. Design and methods: Jump to section Background: Design and methods: Results: Conclusions: Introduction Methods Results Discussion Conclusions Transparency A multi-center, cross-sectional survey enrolled 1002 dyslipidemic patients (August 2010 – January 2011) on LLAs for ≥3 months. Collection of data and blood samples was done over one visit. Physicians and patients filled out questionnaires pertaining to dyslipidemia diagnosis and treatment. LDL-C target levels were defined according to international guidelines. Results: Jump to section Background: Design and methods: Results: Conclusions: Introduction Methods Results Discussion Conclusions Transparency The full analysis set included 992 patients. Mean age was 58.0 ± 11.6 years (41% women, 65.7% diabetics and 51.5% had history of coronary heart disease). LLAs were prescribed for primary prevention or secondary prevention or familial hypercholesterolemia in 45.8% and 52.8% and 1.4% of patients; respectively. Overall, 64.0% and 56.8% of the patients attained their LDL-C goal recommended by the NCEP ATP III and TJETF guidelines, respectively. According to the 2004 NCEP ATP III updated guidelines, about 24.8% of the very high risk group attained their LDL goal of ≤70 mg/dL. Smoking, diabetes, metabolic syndrome, history of cardiovascular disease, increased waist circumference, and elevated pre-treatment LDL-C level were all associated with not reaching LDL-C goals. Conclusions: Jump to section Background: Design and methods: Results: Conclusions: Introduction Methods Results Discussion Conclusions Transparency Although the study cohort was a relatively high risk group and might not be representative of the general population, we found that about 60% of enrolled individuals achieved the LDL-C treatment goals and 24.8% of the very high risk group achieved the recommended LDL-C targets of ≤70 mg/dl; national strategies and aggressive awareness campaigns to effectively control lipid levels to recommended target levels, especially in the high risk groups, are urgently needed.PublishedN/A2016-06-15T07:35:10Z2016-06-15T07:35:10Z20142016-06-15Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0300-7995http://hdl.handle.net/10725/4038http://dx.doi.org/ 10.1007/BF0012365710.1185/03007995.2014.929095Hammoudeh, A. J., Echtay, A., Ghanem, G. Y., & Haddad, J. (2014). Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant: the CEntralized Pan-Levant survey on tHE Undertreatment of hypercholeSterolemia (CEPHEUS) study. Current medical research and opinion, 30(10), 1957-1965.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://www.tandfonline.com/doi/abs/10.1185/03007995.2014.929095enCurrent Medical Research and Opinioninfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/40382021-03-19T10:00:52Z |
| spellingShingle | Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant Ghanem, Georges |
| status_str | publishedVersion |
| title | Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant |
| title_full | Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant |
| title_fullStr | Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant |
| title_full_unstemmed | Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant |
| title_short | Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant |
| title_sort | Achieving low-density lipoprotein cholesterol treatment goals among dyslipidemic individuals in the Levant |
| url | http://hdl.handle.net/10725/4038 http://dx.doi.org/ 10.1007/BF0012365710.1185/03007995.2014.929095 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.tandfonline.com/doi/abs/10.1185/03007995.2014.929095 |