WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells

We examined the role of the actin nucleation promoters neural Wiskott-Aldrich syndrome protein (N-WASP) and WAVE2 in cell protrusion in response to epidermal growth factor (EGF), a key regulator in carcinoma cell invasion. We found that WAVE2 knockdown (KD) suppresses lamellipod formation and increa...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Sarmiento, Corina (author)
مؤلفون آخرون: Wang, Weigang (author), Dovas, Athanassios (author), Yamaguchi, Hideki (author), Sidani, Mazen (author), El-Sibai, Mirvat (author), Desmarais, Vera (author), Holman, Holly A. (author), Kitchen, Susan (author), Backer, Jonathan M. (author), Alberts, Art (author), Condeelis, John (author)
التنسيق: article
منشور في: 2008
الوصول للمادة أونلاين:http://hdl.handle.net/10725/5198
http://dx.doi.org/110.1083/jcb.200708123
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://jcb.rupress.org/content/180/6/1245/tab-pdf
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