The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration

Cell migration involves the localized extension of actinrich protrusions, a process that requires Class I phosphoinositide 3-kinases (PI 3-kinases). Both Rac and Ras have been shown to regulate actin polymerization and activate PI 3-kinase. However, the coordination of Rac, Ras and PI 3-kinase activ...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Yip, Shu-Chin (author)
مؤلفون آخرون:	El-Sibai, Mirvat (author), Coniglio, Salvatore J. (author), Mouneimne, Ghassan (author), Eddy, Robert J. (author), Drees, Beth E. (author), Neilsen, Paul O. (author), Goswami, Sumanta (author), Symons, Marc (author), Condeelis, John S. (author), Backer, Jonathan M. (author)
التنسيق:	article
منشور في:	2007
الوصول للمادة أونلاين:	http://hdl.handle.net/10725/2493 http://dx.doi.org/10.1242/jcs.005298 http://jcs.biologists.org/content/120/17/3138.short
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The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration

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