Stenting for malignant colonic obstruction

Background: Self-expandable metal stent placement for palliation of malignant colonic obstruction for colorectal cancer (CRC) is safe and efficacious. In contrast, outcomes of stent placement for extracolonic malignancy (ECM) are unclear. Objective: To compare the success and complication rates of c...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Azar, Riad (author)
مؤلفون آخرون: Keswani, Rajesh N. (author), Edmundowicz, Steven A. (author), Zhang, Qin (author), Ammar, Tarek (author), Banerjee, Bhaskar (author)
التنسيق: article
منشور في: 2009
الوصول للمادة أونلاين:http://hdl.handle.net/10725/4107
http://dx.doi.org/10.1016/j.gie.2008.09.009
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.giejournal.org/article/S0016-5107(08)02590-X/abstract
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author Azar, Riad
author2 Keswani, Rajesh N.
Edmundowicz, Steven A.
Zhang, Qin
Ammar, Tarek
Banerjee, Bhaskar
author2_role author
author
author
author
author
author_facet Azar, Riad
Keswani, Rajesh N.
Edmundowicz, Steven A.
Zhang, Qin
Ammar, Tarek
Banerjee, Bhaskar
author_role author
dc.creator.none.fl_str_mv Azar, Riad
Keswani, Rajesh N.
Edmundowicz, Steven A.
Zhang, Qin
Ammar, Tarek
Banerjee, Bhaskar
dc.date.none.fl_str_mv 2009
2016-06-20T09:52:49Z
2016-06-20T09:52:49Z
2016-06-20
dc.identifier.none.fl_str_mv 0016-5107
http://hdl.handle.net/10725/4107
http://dx.doi.org/10.1016/j.gie.2008.09.009
Keswani, R. N., Azar, R. R., Edmundowicz, S. A., Zhang, Q., Ammar, T., Banerjee, B., ... & Jonnalagadda, S. S. (2009). Stenting for malignant colonic obstruction: a comparison of efficacy and complications in colonic versus extracolonic malignancy. Gastrointestinal endoscopy, 69(3), 675-680.
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.giejournal.org/article/S0016-5107(08)02590-X/abstract
dc.language.none.fl_str_mv en
dc.relation.none.fl_str_mv Gastrointestinal Endoscopy
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv Stenting for malignant colonic obstruction
a comparison of efficacy and complications in colonic versus extracolonic malignancy
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Background: Self-expandable metal stent placement for palliation of malignant colonic obstruction for colorectal cancer (CRC) is safe and efficacious. In contrast, outcomes of stent placement for extracolonic malignancy (ECM) are unclear. Objective: To compare the success and complication rates of colorectal stenting in patients with CRC versus those with ECM. Design: Retrospective chart review. Setting: Tertiary-care academic medical center. Patients and Interventions: Between September 2000 and December 2007, all patients with malignant colon obstruction in whom endoscopy was performed with the intention of placing a colonic metal stent. Main Outcome Measurements: Technical and clinical success rates, surgical interventions, and procedure related complications. Results: Colonic stenting was performed for CRC in 34 patients and for ECM in 15 patients. Patients with CRC were more likely to have clinical success after all endoscopic therapy (94.1%) than those with ECM (20.0%) (P ! .0001). Surgical diversion to relieve persistent obstructive symptoms was required in significantly more patients with ECM. Five patients with ECM (33.3%) had at least one complication, including 2 deaths, compared with 3 patients with CRC (8.8%) (P Z .046). Only underlying ECM was predictive of failed colon stent placement by multivariate analysis (hazard ratio 21.0, P Z .0013). A history of radiation therapy was the sole predictor of complications (hazard ratio 7.8, P Z .048). Limitations: Single institution, retrospective analysis, relatively small sample size. Conclusions: Colon stenting for large-bowel obstruction from ECM is infrequently successful and is associated with a significantly higher risk of complications in comparison with patients with CRC.
eu_rights_str_mv openAccess
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Keswani, R. N., Azar, R. R., Edmundowicz, S. A., Zhang, Q., Ammar, T., Banerjee, B., ... & Jonnalagadda, S. S. (2009). Stenting for malignant colonic obstruction: a comparison of efficacy and complications in colonic versus extracolonic malignancy. Gastrointestinal endoscopy, 69(3), 675-680.
language_invalid_str_mv en
network_acronym_str LAURepo
network_name_str Lebanese American University repository
oai_identifier_str oai:laur.lau.edu.lb:10725/4107
publishDate 2009
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spelling Stenting for malignant colonic obstructiona comparison of efficacy and complications in colonic versus extracolonic malignancyAzar, RiadKeswani, Rajesh N.Edmundowicz, Steven A.Zhang, QinAmmar, TarekBanerjee, BhaskarBackground: Self-expandable metal stent placement for palliation of malignant colonic obstruction for colorectal cancer (CRC) is safe and efficacious. In contrast, outcomes of stent placement for extracolonic malignancy (ECM) are unclear. Objective: To compare the success and complication rates of colorectal stenting in patients with CRC versus those with ECM. Design: Retrospective chart review. Setting: Tertiary-care academic medical center. Patients and Interventions: Between September 2000 and December 2007, all patients with malignant colon obstruction in whom endoscopy was performed with the intention of placing a colonic metal stent. Main Outcome Measurements: Technical and clinical success rates, surgical interventions, and procedure related complications. Results: Colonic stenting was performed for CRC in 34 patients and for ECM in 15 patients. Patients with CRC were more likely to have clinical success after all endoscopic therapy (94.1%) than those with ECM (20.0%) (P ! .0001). Surgical diversion to relieve persistent obstructive symptoms was required in significantly more patients with ECM. Five patients with ECM (33.3%) had at least one complication, including 2 deaths, compared with 3 patients with CRC (8.8%) (P Z .046). Only underlying ECM was predictive of failed colon stent placement by multivariate analysis (hazard ratio 21.0, P Z .0013). A history of radiation therapy was the sole predictor of complications (hazard ratio 7.8, P Z .048). Limitations: Single institution, retrospective analysis, relatively small sample size. Conclusions: Colon stenting for large-bowel obstruction from ECM is infrequently successful and is associated with a significantly higher risk of complications in comparison with patients with CRC.PublishedN/A2016-06-20T09:52:49Z2016-06-20T09:52:49Z20092016-06-20Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0016-5107http://hdl.handle.net/10725/4107http://dx.doi.org/10.1016/j.gie.2008.09.009Keswani, R. N., Azar, R. R., Edmundowicz, S. A., Zhang, Q., Ammar, T., Banerjee, B., ... & Jonnalagadda, S. S. (2009). Stenting for malignant colonic obstruction: a comparison of efficacy and complications in colonic versus extracolonic malignancy. Gastrointestinal endoscopy, 69(3), 675-680.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://www.giejournal.org/article/S0016-5107(08)02590-X/abstractenGastrointestinal Endoscopyinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/41072021-03-19T10:00:55Z
spellingShingle Stenting for malignant colonic obstruction
Azar, Riad
status_str publishedVersion
title Stenting for malignant colonic obstruction
title_full Stenting for malignant colonic obstruction
title_fullStr Stenting for malignant colonic obstruction
title_full_unstemmed Stenting for malignant colonic obstruction
title_short Stenting for malignant colonic obstruction
title_sort Stenting for malignant colonic obstruction
url http://hdl.handle.net/10725/4107
http://dx.doi.org/10.1016/j.gie.2008.09.009
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.giejournal.org/article/S0016-5107(08)02590-X/abstract