Synthesis of DNA-Sequence-Selective Hairpin Polyamide Platinum Complexes

Two DNA-sequence-selective hairpin polyamide platinum(II) complexes, containing pyrrole and imidazole heterocyclic rings, have been synthesised by different methods. A six-ring complex, selective for (A/T)GGG(A/T) DNA sequences, was made by using solid-phase synthesis, whilst an eight-ring complex,...

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Bibliographic Details
Main Author: Taleb, Robin (author)
Other Authors: Jaramillo, David (author), Wheate, Nial (author), Aldrich-Wright, Janice (author)
Format: article
Published: 2007
Online Access:http://hdl.handle.net/10725/3496
http://dx.doi.org/10.1002/chem.200601486
http://onlinelibrary.wiley.com/doi/10.1002/chem.200601486/full
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