Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
We previously showed that inhibition of the platelet-derived growth factor receptor (PDGFR) blocks the survival and migration of medulloblastoma cells. Identification of in vitro PDGFR-targeting pharmacologic agents that are suitable for preclinical testing in medulloblastoma models in vivo will be...
Saved in:
| Main Author: | Castellino, R.C. (author) |
|---|---|
| Other Authors: | MacDonald, T.J. (author), Abouantoun, Thamara J. (author) |
| Format: | article |
| Published: |
2011
|
| Online Access: | http://hdl.handle.net/10725/4421 http://dx.doi.org/10.1007/s11060-010-0259-9 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://link.springer.com/article/10.1007/s11060-010-0259-9 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Imatinib blocks migration and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of epidermal growth factor receptor
by: Abouantoun, Thamara J.
Published: (2009) -
L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression
by: Rached, Johnny
Published: (2016) -
Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression
by: Nabeel Abdulrahman (725914)
Published: (2022) -
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
by: Ejlal Abu-El-Rub (5168183)
Published: (2025) -
Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling
by: Sabah Akhtar (5809925)
Published: (2019)