Early growth response factor-1 mediates prostaglandin E2-dependent transcriptional suppression of cytokine-induced tumor necrosis factor-α gene expression in human macrophages and rheumatoid arthritis-affected synovial fibroblasts
Tumor necrosis factor-α (TNF-α) is a pleiotropic proinflammatory cytokine that modulates a broad range of inflammatory and immunological processes. We have investigated the potential immunomodulatory properties of prostaglandin E2 (PGE2) by examining the molecular mechanism by which the eicosanoid s...
محفوظ في:
| المؤلف الرئيسي: | Faour, Wissam (author) |
|---|---|
| مؤلفون آخرون: | Alaaeddine, Nada (author), Mancini, Arturo (author), He, Qing Wen (author), Jovanovic, Dragan (author), Di Battista, John (author) |
| التنسيق: | article |
| منشور في: |
2005
|
| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/2314 http://dx.doi.org/10.1074/jbc.M414067200 http://www.jbc.org/content/280/10/9536.short |
| الوسوم: |
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