Guanine glycation repair by DJ-1/Park7 and its bacterial homologs
DNA damage induced by reactive carbonyls (mainly methylglyoxal and glyoxal), called DNA glycation, is quantitatively as important as oxidative damage. DNA glycation is associated with increased mutation frequency, DNA strand breaks, and cytotoxicity. However, in contrast to guanine oxidation repair,...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | , , , , , , |
| Format: | article |
| Published: |
2017
|
| Online Access: | http://hdl.handle.net/10725/10677 https://doi.org/10.1126/science.aag1095 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://science.sciencemag.org/content/357/6347/208/tab-article-info |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|