Proteomic analysis of a candida albicans pga1 null strain
We previously characterized Pga1, a Candida albicans (C. albicans) cell wall protein necessary for proper virulence, adhesion, and resistance to oxidative stress. By utilizing tandem mass spectrometry coupled with bioinformatics to investigate cell wall proteome expression in a pga1 null fourteen an...
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2018
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| Online Access: | http://hdl.handle.net/10725/8458 https://doi.org/10.1016/j.euprot.2018.02.001 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/S2212968517300065 |
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| _version_ | 1864513484959514624 |
|---|---|
| author | Awad, Andy |
| author2 | El Khoury, Pamela Wex, Brigitte Khalaf, Roy A. |
| author2_role | author author author |
| author_facet | Awad, Andy El Khoury, Pamela Wex, Brigitte Khalaf, Roy A. |
| author_role | author |
| dc.creator.none.fl_str_mv | Awad, Andy El Khoury, Pamela Wex, Brigitte Khalaf, Roy A. |
| dc.date.none.fl_str_mv | 2018-09-13T11:03:16Z 2018-09-13T11:03:16Z 2018 2018-09-13 |
| dc.identifier.none.fl_str_mv | 2212-9685 http://hdl.handle.net/10725/8458 https://doi.org/10.1016/j.euprot.2018.02.001 Awad, A., El Khoury, P., Wex, B., & Khalaf, R. A. (2018). Proteomic analysis of a Candida albicans pga1 Null Strain. EuPA open proteomics. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/S2212968517300065 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | EuPA Open Proteomics |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Proteomic analysis of a candida albicans pga1 null strain |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | We previously characterized Pga1, a Candida albicans (C. albicans) cell wall protein necessary for proper virulence, adhesion, and resistance to oxidative stress. By utilizing tandem mass spectrometry coupled with bioinformatics to investigate cell wall proteome expression in a pga1 null fourteen and 36 proteins were identified in the wild type grown under filamentous and non-filamentous conditions respectively, but were not detected in the mutant, including members of the PGA GPI anchored family. Virulence and adhesion proteins such as Hsp 90, Sap10, Cdc11, Int 3 and members of the lipase family were also identified exclusively in the wild type. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_daf49fef91993ff181e65fbc78de7c93 |
| identifier_str_mv | 2212-9685 Awad, A., El Khoury, P., Wex, B., & Khalaf, R. A. (2018). Proteomic analysis of a Candida albicans pga1 Null Strain. EuPA open proteomics. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/8458 |
| publishDate | 2018 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Proteomic analysis of a candida albicans pga1 null strainAwad, AndyEl Khoury, PamelaWex, BrigitteKhalaf, Roy A.We previously characterized Pga1, a Candida albicans (C. albicans) cell wall protein necessary for proper virulence, adhesion, and resistance to oxidative stress. By utilizing tandem mass spectrometry coupled with bioinformatics to investigate cell wall proteome expression in a pga1 null fourteen and 36 proteins were identified in the wild type grown under filamentous and non-filamentous conditions respectively, but were not detected in the mutant, including members of the PGA GPI anchored family. Virulence and adhesion proteins such as Hsp 90, Sap10, Cdc11, Int 3 and members of the lipase family were also identified exclusively in the wild type.PublishedN/A2018-09-13T11:03:16Z2018-09-13T11:03:16Z20182018-09-13Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2212-9685http://hdl.handle.net/10725/8458https://doi.org/10.1016/j.euprot.2018.02.001Awad, A., El Khoury, P., Wex, B., & Khalaf, R. A. (2018). Proteomic analysis of a Candida albicans pga1 Null Strain. EuPA open proteomics.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://www.sciencedirect.com/science/article/pii/S2212968517300065enEuPA Open Proteomicsinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/84582021-03-19T10:43:21Z |
| spellingShingle | Proteomic analysis of a candida albicans pga1 null strain Awad, Andy |
| status_str | publishedVersion |
| title | Proteomic analysis of a candida albicans pga1 null strain |
| title_full | Proteomic analysis of a candida albicans pga1 null strain |
| title_fullStr | Proteomic analysis of a candida albicans pga1 null strain |
| title_full_unstemmed | Proteomic analysis of a candida albicans pga1 null strain |
| title_short | Proteomic analysis of a candida albicans pga1 null strain |
| title_sort | Proteomic analysis of a candida albicans pga1 null strain |
| url | http://hdl.handle.net/10725/8458 https://doi.org/10.1016/j.euprot.2018.02.001 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/S2212968517300065 |