Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases
Some investigators have suggested that wedge resection (WR) confers a higher incidence of positive margins and an inferior survival compared with anatomic resection (AR) of colorectal liver metastases (CLM). We sought to investigate the margin status, pattern of recurrence, and overall survival of p...
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| مؤلفون آخرون: | , , , , , , , , |
| التنسيق: | article |
| منشور في: |
2006
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/2550 http://dx.doi.org/10.1016/j.gassur.2005.07.022 http://link.springer.com/article/10.1016/j.gassur.2005.07.022 |
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| _version_ | 1864513458624528384 |
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| author | Zorzi, Daria |
| author2 | Mullen, John T. Abdalla, Eddie K. Pawlik, Timothy M. Andres, Axel Muratore, Andrea Curley, Steven A. Mentha, Gilles Capussotti, Lorenzo Vauthey, Jean-Nicolas |
| author2_role | author author author author author author author author author |
| author_facet | Zorzi, Daria Mullen, John T. Abdalla, Eddie K. Pawlik, Timothy M. Andres, Axel Muratore, Andrea Curley, Steven A. Mentha, Gilles Capussotti, Lorenzo Vauthey, Jean-Nicolas |
| author_role | author |
| dc.creator.none.fl_str_mv | Zorzi, Daria Mullen, John T. Abdalla, Eddie K. Pawlik, Timothy M. Andres, Axel Muratore, Andrea Curley, Steven A. Mentha, Gilles Capussotti, Lorenzo Vauthey, Jean-Nicolas |
| dc.date.none.fl_str_mv | 2006 2006-01 2015-11-12T12:08:04Z 2015-11-12T12:08:04Z |
| dc.identifier.none.fl_str_mv | 1091-255X http://hdl.handle.net/10725/2550 http://dx.doi.org/10.1016/j.gassur.2005.07.022 Zorzi, D., Mullen, J. T., Abdalla, E. K., Pawlik, T. M., Andres, A., Muratore, A., ... & Vauthey, J. N. (2006). Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases. Journal of Gastrointestinal Surgery, 10(1), 86-94. http://link.springer.com/article/10.1016/j.gassur.2005.07.022 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Journal of Gastrointestinal Surgery |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Some investigators have suggested that wedge resection (WR) confers a higher incidence of positive margins and an inferior survival compared with anatomic resection (AR) of colorectal liver metastases (CLM). We sought to investigate the margin status, pattern of recurrence, and overall survival of patients with CLM treated with WR or AR. We identified 253 consecutive patients, in a multi-institutional database from 1991 to 2004, who underwent either WR or AR. WR was defined as a nonanatomic resection of the CLM, and AR was defined as single or multiple resections of one or two contiguous Couinaud segments. Clinicopathologic factors were analyzed with regard to pattern of recurrence and survival. One hundred six WRs were performed in 72 patients and 194 ARs in 181 patients. There was no difference in the rate of positive surgical margin (8.3%), overall recurrence rates, or patterns of recurrence between patients treated with WR vs. AR. Patients who had a positive surgical resection margin were more likely to recur at the surgical margin regardless of whether they underwent WR or AR. The median survival was 76.6 months for WR and 80.8 months for AR, with 5-year actuarial survival rates of 61% and 60%, respectively. AR is not superior to WR in terms of tumor clearance, pattern of recurrence, or survival. WR should remain an integral component of the surgical treatment of CLM. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_dd6a62027e5f2ebecbcbab25224f5d4a |
| identifier_str_mv | 1091-255X Zorzi, D., Mullen, J. T., Abdalla, E. K., Pawlik, T. M., Andres, A., Muratore, A., ... & Vauthey, J. N. (2006). Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases. Journal of Gastrointestinal Surgery, 10(1), 86-94. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/2550 |
| publishDate | 2006 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastasesZorzi, DariaMullen, John T.Abdalla, Eddie K.Pawlik, Timothy M.Andres, AxelMuratore, AndreaCurley, Steven A.Mentha, GillesCapussotti, LorenzoVauthey, Jean-NicolasSome investigators have suggested that wedge resection (WR) confers a higher incidence of positive margins and an inferior survival compared with anatomic resection (AR) of colorectal liver metastases (CLM). We sought to investigate the margin status, pattern of recurrence, and overall survival of patients with CLM treated with WR or AR. We identified 253 consecutive patients, in a multi-institutional database from 1991 to 2004, who underwent either WR or AR. WR was defined as a nonanatomic resection of the CLM, and AR was defined as single or multiple resections of one or two contiguous Couinaud segments. Clinicopathologic factors were analyzed with regard to pattern of recurrence and survival. One hundred six WRs were performed in 72 patients and 194 ARs in 181 patients. There was no difference in the rate of positive surgical margin (8.3%), overall recurrence rates, or patterns of recurrence between patients treated with WR vs. AR. Patients who had a positive surgical resection margin were more likely to recur at the surgical margin regardless of whether they underwent WR or AR. The median survival was 76.6 months for WR and 80.8 months for AR, with 5-year actuarial survival rates of 61% and 60%, respectively. AR is not superior to WR in terms of tumor clearance, pattern of recurrence, or survival. WR should remain an integral component of the surgical treatment of CLM.PublishedN/A2015-11-12T12:08:04Z2015-11-12T12:08:04Z20062006-01Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1091-255Xhttp://hdl.handle.net/10725/2550http://dx.doi.org/10.1016/j.gassur.2005.07.022Zorzi, D., Mullen, J. T., Abdalla, E. K., Pawlik, T. M., Andres, A., Muratore, A., ... & Vauthey, J. N. (2006). Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases. Journal of Gastrointestinal Surgery, 10(1), 86-94.http://link.springer.com/article/10.1016/j.gassur.2005.07.022enJournal of Gastrointestinal Surgeryinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/25502025-12-17T09:33:26Z |
| spellingShingle | Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases Zorzi, Daria |
| status_str | publishedVersion |
| title | Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases |
| title_full | Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases |
| title_fullStr | Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases |
| title_full_unstemmed | Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases |
| title_short | Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases |
| title_sort | Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases |
| url | http://hdl.handle.net/10725/2550 http://dx.doi.org/10.1016/j.gassur.2005.07.022 http://link.springer.com/article/10.1016/j.gassur.2005.07.022 |