Entry of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine into the rat brain
We studied blood-to-brain entry of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 1-methyl-4-phenylpyridinium (MPP+) and butanol in anesthetized rats using the indicator-fractionation method with right atrial bolus injection. Minimal amounts of MPP+, which has low octanol/water partition coeff...
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1989
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| Online Access: | http://hdl.handle.net/10725/10430 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://jpet.aspetjournals.org/content/249/3/744.short |
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