Prognosis and biology in esthesioneuroblastoma: the emerging role of Hyams grading system
Esthesioneuroblastoma is a sinonasal tumor with distinct clinicopathologic features, multiple facets, and a spectrum of behavior. Characterization of this disease is challenging, and clinically, several staging systems have been used with no consensus on a single scheme. Recently, the Hyams histolog...
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| Format: | article |
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2015
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| Online Access: | http://hdl.handle.net/10725/6151 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://journals.viamedica.pl/oncology_in_clinical_practice/article/view/41427 |
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| Summary: | Esthesioneuroblastoma is a sinonasal tumor with distinct clinicopathologic features, multiple facets, and a spectrum of behavior. Characterization of this disease is challenging, and clinically, several staging systems have been used with no consensus on a single scheme. Recently, the Hyams histological grading system has emerged as a promising prognostication tool that offers an added value to stage. This review addresses prognosis and biology in esthesioneuroblastoma. More specifically, we sought to present a critical appraisal on the value of each of these stratification systems, stage vs. grade, in identifying risk groups and guiding management. |
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