An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals

Background Venous thromboembolism (VTE) is a major cause of death among hospitalized patients. Many VTE prophylaxis guidelines have been developed, including the American College of Chest Physicians (ACCP). VTE prophylaxis is required in specific patients; however, its practice is not always optimal...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Dimassi, Hani (author)
مؤلفون آخرون: Zeitoun, Abeer A. (author), El-Kary, Dania Y. (author), Akel, Marwan G. (author)
التنسيق: article
منشور في: 2015
الوصول للمادة أونلاين:http://hdl.handle.net/10725/2223
http://dx.doi.org/10.1007/s11239-008-0298-7
http://link.springer.com/article/10.1007/s11239-008-0298-7
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author Dimassi, Hani
author2 Zeitoun, Abeer A.
El-Kary, Dania Y.
Akel, Marwan G.
author2_role author
author
author
author_facet Dimassi, Hani
Zeitoun, Abeer A.
El-Kary, Dania Y.
Akel, Marwan G.
author_role author
dc.creator.none.fl_str_mv Dimassi, Hani
Zeitoun, Abeer A.
El-Kary, Dania Y.
Akel, Marwan G.
dc.date.none.fl_str_mv 2015-09-30T13:01:25Z
2015-09-30T13:01:25Z
2015-09-30
dc.identifier.none.fl_str_mv 0929-5305
http://hdl.handle.net/10725/2223
http://dx.doi.org/10.1007/s11239-008-0298-7
Zeitoun, A. A., Dimassi, H. I., El Kary, D. Y., & Akel, M. G. (2009). An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals. Journal of thrombosis and thrombolysis, 28(2), 192-199.
http://link.springer.com/article/10.1007/s11239-008-0298-7
dc.language.none.fl_str_mv en
dc.relation.none.fl_str_mv Journal of thrombosis and thrombolysis
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Background Venous thromboembolism (VTE) is a major cause of death among hospitalized patients. Many VTE prophylaxis guidelines have been developed, including the American College of Chest Physicians (ACCP). VTE prophylaxis is required in specific patients; however, its practice is not always optimal, and often depends on the hospitals’ protocols. In Lebanon, information about the appropriateness of VTE prophylaxis in health care centers is lacking. Objective The primary objective of this study was to evaluate the pattern of VTE prophylaxis application, including agents, doses, duration of treatment, and route of administration, in Lebanese health care centers. Methods A Lebanese multi-center, prospective, chart review study was conducted over 4 months. Data on demographics, VTE prophylaxis medication, dose, route, duration, and associated risk factors were collected by pharmacy students. The appropriateness of VTE prophylaxis was determined as per ACCP guidelines. Patients receiving VTE treatment were excluded from the study. Institutional review board (IRB) approval was obtained from each hospital center. Results A total of 840 patients were included. Both gender groups were equally represented in the sample and the mean age was 59 ± 19.53 years. The majority (639/840, 76.1%) of the sample were at high risk for deep venous thrombosis (DVT), and inappropriate VTE prophylaxis was reported in 35% of the low-risk group, in 70% of the moderate-risk group, and in 39% of the high-risk group (P < 0.0001). Comparing proper VTE prophylaxis practice between intensive care unit (ICU) and non-ICU patients, there was no statistical difference observed in teaching hospitals (67.2% vs. 65.5%, P = 0.312). However, in non-teaching hospitals, appropriate VTE prophylaxis practice was more prevalent in ICU than non-ICU patients (65.9% vs. 51.2%, P = 0.004). The average duration of VTE prophylaxis was less than 10 days. Missing data was a major limitation for this study, where, for instance, the duration of prophylaxis could not be accurately abstracted in half of the sample. Another limitation was the absence of laboratory results needed for clinical assessment of the regimen used. Conclusion This study reflected the importance of assessing VTE prophylaxis in Lebanese hospitals, thus, the need for implementing established guidelines to improve the overall patient safety.
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identifier_str_mv 0929-5305
Zeitoun, A. A., Dimassi, H. I., El Kary, D. Y., & Akel, M. G. (2009). An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals. Journal of thrombosis and thrombolysis, 28(2), 192-199.
language_invalid_str_mv en
network_acronym_str LAURepo
network_name_str Lebanese American University repository
oai_identifier_str oai:laur.lau.edu.lb:10725/2223
publishDate 2015
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spelling An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitalsDimassi, HaniZeitoun, Abeer A.El-Kary, Dania Y.Akel, Marwan G.Background Venous thromboembolism (VTE) is a major cause of death among hospitalized patients. Many VTE prophylaxis guidelines have been developed, including the American College of Chest Physicians (ACCP). VTE prophylaxis is required in specific patients; however, its practice is not always optimal, and often depends on the hospitals’ protocols. In Lebanon, information about the appropriateness of VTE prophylaxis in health care centers is lacking. Objective The primary objective of this study was to evaluate the pattern of VTE prophylaxis application, including agents, doses, duration of treatment, and route of administration, in Lebanese health care centers. Methods A Lebanese multi-center, prospective, chart review study was conducted over 4 months. Data on demographics, VTE prophylaxis medication, dose, route, duration, and associated risk factors were collected by pharmacy students. The appropriateness of VTE prophylaxis was determined as per ACCP guidelines. Patients receiving VTE treatment were excluded from the study. Institutional review board (IRB) approval was obtained from each hospital center. Results A total of 840 patients were included. Both gender groups were equally represented in the sample and the mean age was 59 ± 19.53 years. The majority (639/840, 76.1%) of the sample were at high risk for deep venous thrombosis (DVT), and inappropriate VTE prophylaxis was reported in 35% of the low-risk group, in 70% of the moderate-risk group, and in 39% of the high-risk group (P < 0.0001). Comparing proper VTE prophylaxis practice between intensive care unit (ICU) and non-ICU patients, there was no statistical difference observed in teaching hospitals (67.2% vs. 65.5%, P = 0.312). However, in non-teaching hospitals, appropriate VTE prophylaxis practice was more prevalent in ICU than non-ICU patients (65.9% vs. 51.2%, P = 0.004). The average duration of VTE prophylaxis was less than 10 days. Missing data was a major limitation for this study, where, for instance, the duration of prophylaxis could not be accurately abstracted in half of the sample. Another limitation was the absence of laboratory results needed for clinical assessment of the regimen used. Conclusion This study reflected the importance of assessing VTE prophylaxis in Lebanese hospitals, thus, the need for implementing established guidelines to improve the overall patient safety.PublishedN/A2015-09-30T13:01:25Z2015-09-30T13:01:25Z2015-09-30Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0929-5305http://hdl.handle.net/10725/2223http://dx.doi.org/10.1007/s11239-008-0298-7Zeitoun, A. A., Dimassi, H. I., El Kary, D. Y., & Akel, M. G. (2009). An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals. Journal of thrombosis and thrombolysis, 28(2), 192-199.http://link.springer.com/article/10.1007/s11239-008-0298-7enJournal of thrombosis and thrombolysisinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/22232019-03-04T12:52:15Z
spellingShingle An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals
Dimassi, Hani
status_str publishedVersion
title An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals
title_full An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals
title_fullStr An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals
title_full_unstemmed An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals
title_short An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals
title_sort An evaluation of practice pattern for venous thromboembolism prevention in Lebanese hospitals
url http://hdl.handle.net/10725/2223
http://dx.doi.org/10.1007/s11239-008-0298-7
http://link.springer.com/article/10.1007/s11239-008-0298-7