Role of PDE3 and PDE4 for β-adrenergic control of cAMP and ICa,L in adult rat ventricular myocytes
β-Adrenergic stimulation increases cAMP in cardiac cells to induce PKA-mediated phosphorylation of various proteins regulating heart function, such as the L-type Ca 2+ channels which carry I Ca,L and trigger cardiac contraction. Phosphodiesterases (PDEs) 3 and 4 are the main cAMP degrading enzymes i...
محفوظ في:
| المؤلف الرئيسي: | Leroy, Jerome (author) |
|---|---|
| مؤلفون آخرون: | Abi-Gerges, Aniella (author), Richter, Wito (author), Nikolaev, Viacheslav O. (author), Engelhardt, Stefan (author), Lohse, Martin J. (author), Conti, Marco (author), Fischmeister, Rodolphe (author), Vandecasteele, Gregoire (author) |
| التنسيق: | article |
| منشور في: |
2007
|
| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/6362 http://dx.doi.org/10.1117/j.yjmcc.2007.03.139 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.jmmc-online.com/article/S0022-2828(07)00195-2/abstract#articleInformation |
| الوسوم: |
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مواد مشابهة
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