A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells

The activation of signal transducer and activator of transcription 3 (STAT3) has been identified as a key mediator that drives the fundamental components of melanoma malignancy, including immune suppression in melanoma patients. Increasing evidence also suggests that regulatory T cells (Tregs) are i...

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Bibliographic Details
Main Author: Abou-Ghazal, Mohamed K. (author)
Other Authors: Kong, Ling-Yuan (author), Wei, Jun (author), Sharma, Amit K. (author), Barr, Jason (author), Fokt, Izabela (author), Weinberg, Jeffrey (author), Rao, Ganesh (author), Grimm, Elizabeth (author), Priebe, Waldemar (author), Heimberger, Amy B. (author)
Format: article
Published: 2008
Online Access:http://hdl.handle.net/10725/6475
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://link.springer.com/article/10.1007/s00262-008-0618-y
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