A urokinase-activated recombinant anthrax toxin is selectively cytotoxic to many human tumor cell types
Urokinase plasminogen activator (uPA) is a tumor-specific protease highly expressed in several types of solid tumors and rarely present on normal cells under physiologic conditions. Due to its high expression on metastatic tumors, several different strategies have been used to target the urokinase s...
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| Main Author: | Abi-Habib, Ralph J. (author) |
|---|---|
| Other Authors: | Singh, Ravibhushan (author), Liu, Shihui (author), Bugge, Thomas (author), Leppla, Stephen H. (author), Frankel, Arthur (author) |
| Format: | article |
| Published: |
2006
|
| Online Access: | http://hdl.handle.net/10725/2744 http://dx.doi.org/ 10.1158/1535-7163.MCT-06-0315 http://mct.aacrjournals.org/content/5/10/2556.short |
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