A leukemoid reaction in a patient with a dedifferentiated liposarcoma

This section features outstanding photographs of clinical materials selected for their educational value or message, or possibly their rarity. The images are accompanied by brief case reports (limit 2 typed pages, 4 references). Our readers are invited to submit items for consideration. The patient...

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Bibliographic Details
Main Author: Nasser, Selim M. (author)
Other Authors: Choudry, Umar H. (author), Nielsen, Gunnlaugur P. (author), Ott, Mark J. (author)
Format: article
Published: 2001
Online Access:http://hdl.handle.net/10725/5163
http://dx.doi.org/10.1067/msy.2001.109498
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.sciencedirect.com/science/article/pii/S0039606001366345?np=y&npKey=a3316046f706ab1f7f05cd6d1d2fb80b204019a6cfc434c4b22bfba0925124c8
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Summary:This section features outstanding photographs of clinical materials selected for their educational value or message, or possibly their rarity. The images are accompanied by brief case reports (limit 2 typed pages, 4 references). Our readers are invited to submit items for consideration. The patient was a 63-year-old man who in 1992 went to an outside hospital with vague abdominal discomfort. A computed tomography (CT) scan demonstrated a 4-cm mass near the tail of the pancreas. Laboratory studies revealed a white blood cell count (WBC) of 22,600/mL. The mass was excised, including a distal pancreatectomy and splenectomy. Postoperatively, the patient's WBC normalized. Histology was read as a nonspecific inflammatory process. In 1996 he went to the outside hospital with an episode of upper gastrointestinal bleeding and ongoing melena. His laboratory findings revealed a WBC count of 33,000/mL and a hemoglobin level of 4 g/dL. Upper endoscopy demonstrated a mass eroding into the greater curvature of the stomach. After stabilization, a subtotal gastrectomy with partial excision of a retroperitoneal mass was performed. Histology demonstrated a low-grade malignant fibrous histiocytoma (MFH). The patient recovered, but his WBC remained elevated. A CT scan demonstrated a residual 14-cm retroperitoneal mass. The tumor was thought to be unresectable, and the patient was offered no further therapy.