Metastatic adenocarcinoma to the brain

PURPOSE To describe the appearance on T2-weighted scans of metastatic adenocarcinoma to the brain and to show that the hypointensity frequently associated with these lesions is not related to the presence of mucin, blood products, iron, or calcium. METHODS The MR scans of 14 patients with metastatic...

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Main Author: Carrier, D.A. (author)
Other Authors: Mawad, M.E. (author), Kirkpatrick, J.B. (author), Schmid, M.F. (author)
Format: article
Published: 1994
Online Access:http://hdl.handle.net/10725/11006
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.ajnr.org/content/15/1/155.short
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author Carrier, D.A.
author2 Mawad, M.E.
Kirkpatrick, J.B.
Schmid, M.F.
author2_role author
author
author
author_facet Carrier, D.A.
Mawad, M.E.
Kirkpatrick, J.B.
Schmid, M.F.
author_role author
dc.creator.none.fl_str_mv Carrier, D.A.
Mawad, M.E.
Kirkpatrick, J.B.
Schmid, M.F.
dc.date.none.fl_str_mv 1994
2019-07-09T08:00:14Z
2019-07-09T08:00:14Z
2019-07-09
dc.identifier.none.fl_str_mv 1936-959X
http://hdl.handle.net/10725/11006
Carrier, D. A., Mawad, M. E., Kirkpatrick, J. B., & Schmid, M. F. (1994). Metastatic adenocarcinoma to the brain: MR with pathologic correlation. American journal of neuroradiology, 15(1), 155-159.
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.ajnr.org/content/15/1/155.short
dc.language.none.fl_str_mv en
dc.relation.none.fl_str_mv American Journal of Neuroradiology
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv Metastatic adenocarcinoma to the brain
MR with pathologic correlation
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description PURPOSE To describe the appearance on T2-weighted scans of metastatic adenocarcinoma to the brain and to show that the hypointensity frequently associated with these lesions is not related to the presence of mucin, blood products, iron, or calcium. METHODS The MR scans of 14 patients with metastatic adenocarcinoma to the brain were reviewed retrospectively. The signal intensity on T2-weighted scans of the solid enhancing portion of the tumors was compared with white matter. Histologic examination of the surgical specimens included special stains to search for calcium, mucin, and iron. RESULTS Eight of nine surgical and all six nonsurgical lesions were either iso- or hypointense to white matter on T2-weighted scans. There was no correlation with tumor histology or the presence of mucin, blood products, iron, or calcium. CONCLUSIONS The presence of a hypointense intraaxial mass on T2-weighted scans strongly suggests the possibility of metastatic adenocarcinoma. The MR appearance is not explained by the presence of mucin, blood products, iron, or calcium. This phenomenon most likely reflects the relaxation parameters of the tissue from which the metastasis arose.
eu_rights_str_mv openAccess
format article
id LAURepo_f90eacc6a1bed0ca1ba9c6089ccfa7d9
identifier_str_mv 1936-959X
Carrier, D. A., Mawad, M. E., Kirkpatrick, J. B., & Schmid, M. F. (1994). Metastatic adenocarcinoma to the brain: MR with pathologic correlation. American journal of neuroradiology, 15(1), 155-159.
language_invalid_str_mv en
network_acronym_str LAURepo
network_name_str Lebanese American University repository
oai_identifier_str oai:laur.lau.edu.lb:10725/11006
publishDate 1994
repository.mail.fl_str_mv
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spelling Metastatic adenocarcinoma to the brainMR with pathologic correlationCarrier, D.A.Mawad, M.E.Kirkpatrick, J.B.Schmid, M.F.PURPOSE To describe the appearance on T2-weighted scans of metastatic adenocarcinoma to the brain and to show that the hypointensity frequently associated with these lesions is not related to the presence of mucin, blood products, iron, or calcium. METHODS The MR scans of 14 patients with metastatic adenocarcinoma to the brain were reviewed retrospectively. The signal intensity on T2-weighted scans of the solid enhancing portion of the tumors was compared with white matter. Histologic examination of the surgical specimens included special stains to search for calcium, mucin, and iron. RESULTS Eight of nine surgical and all six nonsurgical lesions were either iso- or hypointense to white matter on T2-weighted scans. There was no correlation with tumor histology or the presence of mucin, blood products, iron, or calcium. CONCLUSIONS The presence of a hypointense intraaxial mass on T2-weighted scans strongly suggests the possibility of metastatic adenocarcinoma. The MR appearance is not explained by the presence of mucin, blood products, iron, or calcium. This phenomenon most likely reflects the relaxation parameters of the tissue from which the metastasis arose.PublishedN/A2019-07-09T08:00:14Z2019-07-09T08:00:14Z19942019-07-09Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1936-959Xhttp://hdl.handle.net/10725/11006Carrier, D. A., Mawad, M. E., Kirkpatrick, J. B., & Schmid, M. F. (1994). Metastatic adenocarcinoma to the brain: MR with pathologic correlation. American journal of neuroradiology, 15(1), 155-159.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://www.ajnr.org/content/15/1/155.shortenAmerican Journal of Neuroradiologyinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/110062021-03-19T10:45:20Z
spellingShingle Metastatic adenocarcinoma to the brain
Carrier, D.A.
status_str publishedVersion
title Metastatic adenocarcinoma to the brain
title_full Metastatic adenocarcinoma to the brain
title_fullStr Metastatic adenocarcinoma to the brain
title_full_unstemmed Metastatic adenocarcinoma to the brain
title_short Metastatic adenocarcinoma to the brain
title_sort Metastatic adenocarcinoma to the brain
url http://hdl.handle.net/10725/11006
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.ajnr.org/content/15/1/155.short