Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis
Background: Scientists have been investigating efficient interventions to prevent and manage obesity. This network meta-analysis (NMA) compared the effect of different diets [moderate macronutrients (MMs), low fat/high carbohydrate (LFHC), high fat/low carbohydrate (HFLC), and usual diet (UD)] on we...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | , , , , , , |
| Format: | article |
| Published: |
2022
|
| Online Access: | http://hdl.handle.net/10725/16554 https://doi.org/10.3389/fnut.2022.821096 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.821096/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1864513472910327808 |
|---|---|
| author | Jabbour, Jana |
| author2 | Rihawi, Yasmin Khamis, Assem M. Ghamlouche, Layal Tabban, Bayan Safadi, Gloria Hamad, Nour Hadla, Rouba |
| author2_role | author author author author author author author |
| author_facet | Jabbour, Jana Rihawi, Yasmin Khamis, Assem M. Ghamlouche, Layal Tabban, Bayan Safadi, Gloria Hamad, Nour Hadla, Rouba |
| author_role | author |
| dc.creator.none.fl_str_mv | Jabbour, Jana Rihawi, Yasmin Khamis, Assem M. Ghamlouche, Layal Tabban, Bayan Safadi, Gloria Hamad, Nour Hadla, Rouba |
| dc.date.none.fl_str_mv | 2022 2022-04-05 2025-02-12T14:14:11Z 2025-02-12T14:14:11Z |
| dc.identifier.none.fl_str_mv | 2296-861X http://hdl.handle.net/10725/16554 https://doi.org/10.3389/fnut.2022.821096 Jabbour, J., Rihawi, Y., Khamis, A. M., Ghamlouche, L., Tabban, B., Safadi, G., ... & Chakhtoura, M. (2022). Long term weight loss diets and obesity indices: results of a network meta-analysis. Frontiers in Nutrition, 9, 1-10. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.821096/full |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Frontiers in Nutrition |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Background: Scientists have been investigating efficient interventions to prevent and manage obesity. This network meta-analysis (NMA) compared the effect of different diets [moderate macronutrients (MMs), low fat/high carbohydrate (LFHC), high fat/low carbohydrate (HFLC), and usual diet (UD)] on weight, body mass index (BMI), and waist circumference (WC) changes at ≥12 months. Methods: We searched Medline, Embase, PubMed databases, and the Cochrane Library. We systematically assessed randomized controlled trials (RCTs) evaluating dietary interventions on adults (mean BMI ≥ 25 kg/m2) receiving active dietary counseling for ≥12 months. We pooled the data using a random-effect NMA. We assessed the quality of the included RCTs using the Cochrane risk of bias (ROB) tool. Results: We included 36 trials, 14 of which compared HFLC with MM diets. Compared with UD, all diets were associated with a significant weight loss (WL) at ≥12 months, HFLC [mean difference in kg (95% CI): −5.5 (−7.6; −3.4)], LFHC [−5.0 (−7.1; −2.9)] and MM [−4.7 (−6.8; −2.7)]. HFLC, compared with MM diet, was associated with a slightly higher WL (of −0.77 kg) and drop in BMI (of −0.36 kg/m2), while no significant difference was detected in other dietary comparisons. WC was lower with all diets compared to UD, with no significant difference across specific diets. There was no significant interaction of the results with the pre-specified sub-groups. The ROB was moderate to high, mostly related to unclear allocation concealment, high dropout rate and unclear or lack of blinding of participants, providers, and outcome assessors. Conclusion: Dietary interventions extending over ≥12 months are superior to UD in inducing weight, BMI and WC loss. HFLC might be associated with a slightly higher WL compared with MM diets. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_fe73b2b57f5863415c714192ae2ea862 |
| identifier_str_mv | 2296-861X Jabbour, J., Rihawi, Y., Khamis, A. M., Ghamlouche, L., Tabban, B., Safadi, G., ... & Chakhtoura, M. (2022). Long term weight loss diets and obesity indices: results of a network meta-analysis. Frontiers in Nutrition, 9, 1-10. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/16554 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-AnalysisJabbour, JanaRihawi, YasminKhamis, Assem M.Ghamlouche, LayalTabban, BayanSafadi, GloriaHamad, NourHadla, RoubaBackground: Scientists have been investigating efficient interventions to prevent and manage obesity. This network meta-analysis (NMA) compared the effect of different diets [moderate macronutrients (MMs), low fat/high carbohydrate (LFHC), high fat/low carbohydrate (HFLC), and usual diet (UD)] on weight, body mass index (BMI), and waist circumference (WC) changes at ≥12 months. Methods: We searched Medline, Embase, PubMed databases, and the Cochrane Library. We systematically assessed randomized controlled trials (RCTs) evaluating dietary interventions on adults (mean BMI ≥ 25 kg/m2) receiving active dietary counseling for ≥12 months. We pooled the data using a random-effect NMA. We assessed the quality of the included RCTs using the Cochrane risk of bias (ROB) tool. Results: We included 36 trials, 14 of which compared HFLC with MM diets. Compared with UD, all diets were associated with a significant weight loss (WL) at ≥12 months, HFLC [mean difference in kg (95% CI): −5.5 (−7.6; −3.4)], LFHC [−5.0 (−7.1; −2.9)] and MM [−4.7 (−6.8; −2.7)]. HFLC, compared with MM diet, was associated with a slightly higher WL (of −0.77 kg) and drop in BMI (of −0.36 kg/m2), while no significant difference was detected in other dietary comparisons. WC was lower with all diets compared to UD, with no significant difference across specific diets. There was no significant interaction of the results with the pre-specified sub-groups. The ROB was moderate to high, mostly related to unclear allocation concealment, high dropout rate and unclear or lack of blinding of participants, providers, and outcome assessors. Conclusion: Dietary interventions extending over ≥12 months are superior to UD in inducing weight, BMI and WC loss. HFLC might be associated with a slightly higher WL compared with MM diets.Published2025-02-12T14:14:11Z2025-02-12T14:14:11Z20222022-04-05Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2296-861Xhttp://hdl.handle.net/10725/16554https://doi.org/10.3389/fnut.2022.821096Jabbour, J., Rihawi, Y., Khamis, A. M., Ghamlouche, L., Tabban, B., Safadi, G., ... & Chakhtoura, M. (2022). Long term weight loss diets and obesity indices: results of a network meta-analysis. Frontiers in Nutrition, 9, 1-10.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.821096/fullenFrontiers in Nutritioninfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/165542025-02-26T14:48:04Z |
| spellingShingle | Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis Jabbour, Jana |
| status_str | publishedVersion |
| title | Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis |
| title_full | Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis |
| title_fullStr | Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis |
| title_full_unstemmed | Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis |
| title_short | Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis |
| title_sort | Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis |
| url | http://hdl.handle.net/10725/16554 https://doi.org/10.3389/fnut.2022.821096 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.821096/full |