Potency and selectivity of a urokinase activated recombinant anthrax toxin to acute myeloid leukemia (AML) cells. (c2015)

Potency and selectivity of a urokinase activated recombinant anthrax toxin to acute myeloid leukemia (AML) cells. (c2015)

Acute myeloid leukemia (AML) is a disorder characterized by uncontrolled mitogenetic activation and proliferation of hematopoietic precursor cells. Up to 30 % of adult patients with AML do not achieve complete remission when treated using chemotherapy. In addition, severe side effects usually limit...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Darwich, Manal El. (author)
التنسيق:	masterThesis
منشور في:	2016
الموضوعات:	Acute Myeloid Leukemia Lebanese American University > Dissertations Dissertations, Academic
الوصول للمادة أونلاين:	http://hdl.handle.net/10725/3598 https://doi.org/10.26756/th.2015.53
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة

The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018)
حسب: Abou Harb, Monica
منشور في: (2018)

Sensitivity of acute myeloid leukemia cells to the dual targeting of the urokinase plasminogen activator and the MAPK pathway by a urokinase-activated anthrax lethal toxin. (c2013)
حسب: Bekdash, Amira
منشور في: (2013)

Targeting human acute myeloid leukemia cells using human recombinant arginase I (Co) - PEG5000 [HuArgl (Co) - PEG5000] - induced arginine depletion. (c2013)
حسب: Tanios, Rita Farid
منشور في: (2013)

Targeting the MAP Kinase pathway in human acute myeloid leukemia cells using a recombinant anthrax lethal toxin. (c2013)
حسب: Kassab, Elias
منشور في: (2013)

In Vitro and In Vivo Effects of Lebanese Cannabis Oil Against Acute Myeloid Leukemia (AML)
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منشور في: (2023)

Mechanisms of Cytotoxicity of Wild-Type Anthrax Lethal Toxin (PrAg/LF) to Acute Myeloid Leukemia Cells: The role of Autophagy
حسب: Sarout, Diamo
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Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute myeloid leukemia
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منشور في: (2023)

Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)
حسب: Azar, Daniel Fadi
منشور في: (2016)

Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF)
حسب: Al Saneh, Ahmad
منشور في: (2020)

Characterization of the Cytotoxic Mechanism and Mode of Cell Death Induced by a MEK1/2-selective version of Anthrax Lethal Toxin (PrAg/LFW271A) in Acute Myeloid Leukemia
حسب: Mroue, Zeinab
منشور في: (2023)

Mechanisms of human recombinant arginase I (Co) - PEG5000 [Huarg I (Co) - PEG5000] - induced cytotoxicity on AML cells. (c2017)
حسب: Assaf, Nicole
منشور في: (2017)

The anticancer effect of β-2 himachalen-6-ol from Lebanese wild carrot on human acute myeloid leukemia cells. (c2016)
حسب: Boulos, Joelle C.
منشور في: (2016)

The Anti-Tumor Effect of Flaxseed Lignan Derivatives on Different Acute Myeloid Leukemia Cancer Cells
حسب: Tannous, Stephanie
منشور في: (2020)

The vitamin E derivative gamma tocotrienol promotes anti-tumor effects in acute myeloid leukemia cell lines. (c2019)
حسب: Mohamad, Maya Riad
منشور في: (2019)

Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells in Vitro
حسب: El Khoury, Marianne
منشور في: (2020)

Sensitivity of acute myeloid leukemia cell lines to the dual targeting of the urokinase system and the mapk pathway by modified anthrax toxins. (c2010)
حسب: Timsah, Zahra S.
منشور في: (2010)

Myelomastocytic transformation in chronic myeloid leukemia blast phase: A case report
حسب: Abdulrahman F. Al-Mashdali (17148316)
منشور في: (2025)

Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
حسب: Taki, Fatima
منشور في: (2020)

Anti-neoplastic Effect of Adjuvant Epigenetic Therapy of Decitabine and Suberoylanilide Hydroxamic Acid on U937 Acute Myeloid Leukemia Cell Line
حسب: Babikian, Patil
منشور في: (2020)

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death
حسب: Tohme, Sara
منشور في: (2023)

Sensitivity of colorectal cancer cells to the recombinant Anthrax lethal toxin and the Urokinase-activated Anthrax lethal toxin. (c2014)
حسب: Kasbo, Zein Jean
منشور في: (2014)

Safety and efficacy of chimeric antigen receptor T-cell therapy for acute myeloid leukemia: A subgroup based meta-analysis
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منشور في: (2024)

Acute Myeloid Leukemia in Qatar (2010–2016): Clinical, Biological, and Prognostic Factors and Treatment Outcomes
حسب: Halima El Omri (14778790)
منشور في: (2020)

Effect of Anthrax Lethal Toxin on Activation of MAPK Pathway and Autophagy in AML Cell Lines
حسب: Soukarieh, Rania
منشور في: (2021)

The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants
حسب: Ana Rio-Machin (19686124)
منشور في: (2020)

Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis
حسب: Nasr, Peter
منشور في: (2020)

Characterization of urokinase plasminogen activator-activated recombinant anthrax toxin for targeted cancer therapy
حسب: Abi-Habib, Ralph J.
منشور في: (2006)

Spontaneous tumor lysis syndrome in a patient with accelerated phase chronic myeloid leukemia treated successfully with rasburicase
حسب: Abdulrahman F. Al-Mashdali (17148316)
منشور في: (2022)

The Effect of Recombinant Anthrax Lethal Toxin on Breast Cancer Cell Motility, Adhesion, and Invasion
حسب: El Chami, Dana
منشور في: (2020)

Dasatinib versus nilotinib as upfront therapy for treatment naïve chronic myeloid leukemia chronic phase
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منشور في: (2021)

A urokinase-activated recombinant anthrax toxin is selectively cytotoxic to many human tumor cell types
حسب: Abi-Habib, Ralph J.
منشور في: (2006)

A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia blasts
حسب: Abi-Habib, Ralph J.
منشور في: (2004)

Mathematical Modeling of Pediatric Leukemia: Logical Modeling Approach
حسب: Lacoste, Valery
منشور في: (2024)

Gene Expression Landscape of Chronic Myeloid Leukemia K562 Cells Overexpressing the Tumor Suppressor Gene PTPRG
حسب: Giulia Lombardi (3944720)
منشور في: (2022)

Differentiation syndrome in patients with acute promyelocytic leukemia
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منشور في: (2023)

Safety and efficacy of tyrosine kinase inhibitors in pediatric chronic myeloid leukemia: A protocol for systematic review and meta-analysis
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منشور في: (2022)

Regulative Loop between β-catenin and Protein Tyrosine Receptor Type γ in Chronic Myeloid Leukemia
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منشور في: (2020)

Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breast Cancer
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Multi-omics and machine learning reveal context-specific gene regulatory activities of PML::RARA in acute promyelocytic leukemia
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Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
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منشور في: (2015)