Prevalence of Depression and Anxiety in Adult Patients with β-Thalassemia Major and Intermedia
Objective: To evaluate and compare the prevalence and risk factors for anxiety and depression in adults with β-thalassemia major (TM) and intermedia (TI). Method: A cross-sectional study of TI and TM patients at a Chronic Care Center in Lebanon. A total of 80 patients agreed to participate (32 TI (m...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , |
| التنسيق: | article |
| منشور في: |
2012
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/6408 https://doi.org/10.2190/PM.44.4.a http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://journals.sagepub.com/doi/abs/10.2190/PM.44.4.a |
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| _version_ | 1864513479787937792 |
|---|---|
| author | Khoury, Brigitte |
| author2 | Musallam, Khaled M. Abi-Habib, Rudy Bazzi, Lama Al Ward, Zainab Succar, Julien Halawi, Racha Hankir, Ahmed |
| author2_role | author author author author author author author |
| author_facet | Khoury, Brigitte Musallam, Khaled M. Abi-Habib, Rudy Bazzi, Lama Al Ward, Zainab Succar, Julien Halawi, Racha Hankir, Ahmed |
| author_role | author |
| dc.creator.none.fl_str_mv | Khoury, Brigitte Musallam, Khaled M. Abi-Habib, Rudy Bazzi, Lama Al Ward, Zainab Succar, Julien Halawi, Racha Hankir, Ahmed |
| dc.date.none.fl_str_mv | 2012 2017-10-23T10:43:09Z 2017-10-23T10:43:09Z 2017-10-23 |
| dc.identifier.none.fl_str_mv | 0091-2174 http://hdl.handle.net/10725/6408 https://doi.org/10.2190/PM.44.4.a Khoury, B., Musallam, K. M., Abi-Habib, R., Bazzi, L., Al Ward, Z., Succar, J., ... & Taher, A. T. (2012). Prevalence of depression and anxiety in adult patients with β-thalassemia major and intermedia. The International Journal of Psychiatry in Medicine, 44(4), 291-303. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://journals.sagepub.com/doi/abs/10.2190/PM.44.4.a |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | The International Journal of Psychiatry in Medicine |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Prevalence of Depression and Anxiety in Adult Patients with β-Thalassemia Major and Intermedia |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Objective: To evaluate and compare the prevalence and risk factors for anxiety and depression in adults with β-thalassemia major (TM) and intermedia (TI). Method: A cross-sectional study of TI and TM patients at a Chronic Care Center in Lebanon. A total of 80 patients agreed to participate (32 TI (median age 24 years) and 48 TM (median age 23 years)). The Beck Depression Inventory (BDI) and State-Trait Anxiety Inventory (STAI) questionnaires were used to assess the depression and anxiety levels of patients, respectively. Data on patient demographics, clinical complications, and socioeconomic status were also collected. Results: Patients with TM had a significantly longer median duration with a known thalassemia diagnosis than patients with TI (p < 0.001). A considerable proportion of patients had depression (35.0%), State (S)-anxiety (22.5%) or Trait (T)-anxiety (36.2%). Patients with TI had a higher median S-anxiety score compared with TM (p = 0.035), although the median T-anxiety and depression scores were similar. On linear regression analysis, the significant association between the thalassemia diagnosis (TM versus TI) and S-anxiety score (beta: 5.740; 95% CI: 0.201 to 11.278; p = 0.042) was no longer observed upon adjustment for the co-variate duration with a known thalassemia diagnosis (beta: 3.162; 95% CI: −2.949 to 9.274; p = 0.306). Conclusions: A considerable proportion of adult patients with TM and TI show evidence of depression and anxiety. Patients with TI are more liable to state anxiety than TM patients of a similar age, which is attributed to a shorter duration of living with a thalassemia diagnosis. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_ffe9c5f199730fe37fa77408c39c6604 |
| identifier_str_mv | 0091-2174 Khoury, B., Musallam, K. M., Abi-Habib, R., Bazzi, L., Al Ward, Z., Succar, J., ... & Taher, A. T. (2012). Prevalence of depression and anxiety in adult patients with β-thalassemia major and intermedia. The International Journal of Psychiatry in Medicine, 44(4), 291-303. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/6408 |
| publishDate | 2012 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Prevalence of Depression and Anxiety in Adult Patients with β-Thalassemia Major and IntermediaKhoury, BrigitteMusallam, Khaled M.Abi-Habib, RudyBazzi, LamaAl Ward, ZainabSuccar, JulienHalawi, RachaHankir, AhmedObjective: To evaluate and compare the prevalence and risk factors for anxiety and depression in adults with β-thalassemia major (TM) and intermedia (TI). Method: A cross-sectional study of TI and TM patients at a Chronic Care Center in Lebanon. A total of 80 patients agreed to participate (32 TI (median age 24 years) and 48 TM (median age 23 years)). The Beck Depression Inventory (BDI) and State-Trait Anxiety Inventory (STAI) questionnaires were used to assess the depression and anxiety levels of patients, respectively. Data on patient demographics, clinical complications, and socioeconomic status were also collected. Results: Patients with TM had a significantly longer median duration with a known thalassemia diagnosis than patients with TI (p < 0.001). A considerable proportion of patients had depression (35.0%), State (S)-anxiety (22.5%) or Trait (T)-anxiety (36.2%). Patients with TI had a higher median S-anxiety score compared with TM (p = 0.035), although the median T-anxiety and depression scores were similar. On linear regression analysis, the significant association between the thalassemia diagnosis (TM versus TI) and S-anxiety score (beta: 5.740; 95% CI: 0.201 to 11.278; p = 0.042) was no longer observed upon adjustment for the co-variate duration with a known thalassemia diagnosis (beta: 3.162; 95% CI: −2.949 to 9.274; p = 0.306). Conclusions: A considerable proportion of adult patients with TM and TI show evidence of depression and anxiety. Patients with TI are more liable to state anxiety than TM patients of a similar age, which is attributed to a shorter duration of living with a thalassemia diagnosis.PublishedN/A2017-10-23T10:43:09Z2017-10-23T10:43:09Z20122017-10-23Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0091-2174http://hdl.handle.net/10725/6408https://doi.org/10.2190/PM.44.4.aKhoury, B., Musallam, K. M., Abi-Habib, R., Bazzi, L., Al Ward, Z., Succar, J., ... & Taher, A. T. (2012). Prevalence of depression and anxiety in adult patients with β-thalassemia major and intermedia. The International Journal of Psychiatry in Medicine, 44(4), 291-303.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://journals.sagepub.com/doi/abs/10.2190/PM.44.4.aenThe International Journal of Psychiatry in Medicineinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/64082021-03-19T10:43:10Z |
| spellingShingle | Prevalence of Depression and Anxiety in Adult Patients with β-Thalassemia Major and Intermedia Khoury, Brigitte |
| status_str | publishedVersion |
| title | Prevalence of Depression and Anxiety in Adult Patients with β-Thalassemia Major and Intermedia |
| title_full | Prevalence of Depression and Anxiety in Adult Patients with β-Thalassemia Major and Intermedia |
| title_fullStr | Prevalence of Depression and Anxiety in Adult Patients with β-Thalassemia Major and Intermedia |
| title_full_unstemmed | Prevalence of Depression and Anxiety in Adult Patients with β-Thalassemia Major and Intermedia |
| title_short | Prevalence of Depression and Anxiety in Adult Patients with β-Thalassemia Major and Intermedia |
| title_sort | Prevalence of Depression and Anxiety in Adult Patients with β-Thalassemia Major and Intermedia |
| url | http://hdl.handle.net/10725/6408 https://doi.org/10.2190/PM.44.4.a http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://journals.sagepub.com/doi/abs/10.2190/PM.44.4.a |