Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future Diagnostics

<h3>Background</h3><p dir="ltr">Artificial intelligence (AI) is transforming dermatopathology by enhancing diagnostic accuracy, efficiency, and precision medicine. Despite its promise, challenges such as dataset biases, underrepresentation of diverse populations, and limi...

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Main Author: Diala Ra'Ed Kamal Kakish (22330627) (author)
Other Authors: Jehad Feras AlSamhori (17746809) (author), Andy Noel Ramirez Fajardo (22330630) (author), Lana N. Qaqish (22330633) (author), Layan Ahmed Jaber (22330636) (author), Rawan Abujudeh (22330639) (author), Mohammad Hathal Mahmoud Al‐Zuriqat (22330642) (author), Amina Yahya Mohammed (22330645) (author), Abdulqadir J. Nashwan (11659453) (author)
Published: 2025
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author Diala Ra'Ed Kamal Kakish (22330627)
author2 Jehad Feras AlSamhori (17746809)
Andy Noel Ramirez Fajardo (22330630)
Lana N. Qaqish (22330633)
Layan Ahmed Jaber (22330636)
Rawan Abujudeh (22330639)
Mohammad Hathal Mahmoud Al‐Zuriqat (22330642)
Amina Yahya Mohammed (22330645)
Abdulqadir J. Nashwan (11659453)
author2_role author
author
author
author
author
author
author
author
author_facet Diala Ra'Ed Kamal Kakish (22330627)
Jehad Feras AlSamhori (17746809)
Andy Noel Ramirez Fajardo (22330630)
Lana N. Qaqish (22330633)
Layan Ahmed Jaber (22330636)
Rawan Abujudeh (22330639)
Mohammad Hathal Mahmoud Al‐Zuriqat (22330642)
Amina Yahya Mohammed (22330645)
Abdulqadir J. Nashwan (11659453)
author_role author
dc.creator.none.fl_str_mv Diala Ra'Ed Kamal Kakish (22330627)
Jehad Feras AlSamhori (17746809)
Andy Noel Ramirez Fajardo (22330630)
Lana N. Qaqish (22330633)
Layan Ahmed Jaber (22330636)
Rawan Abujudeh (22330639)
Mohammad Hathal Mahmoud Al‐Zuriqat (22330642)
Amina Yahya Mohammed (22330645)
Abdulqadir J. Nashwan (11659453)
dc.date.none.fl_str_mv 2025-01-17T09:00:00Z
dc.identifier.none.fl_str_mv 10.1002/der2.70018
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Transforming_Dermatopathology_With_AI_Addressing_Bias_Enhancing_Interpretability_and_Shaping_Future_Diagnostics/30234127
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Health sciences
Health services and systems
Philosophy and religious studies
Applied ethics
artificial Intelligence in dermatopathology
diagnostic bias
explainable AI (XAI)
multimodal diagnostics
precision medicine
dc.title.none.fl_str_mv Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future Diagnostics
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Background</h3><p dir="ltr">Artificial intelligence (AI) is transforming dermatopathology by enhancing diagnostic accuracy, efficiency, and precision medicine. Despite its promise, challenges such as dataset biases, underrepresentation of diverse populations, and limited transparency hinder its widespread adoption. Addressing these gaps can set a new standard for equitable and patient‐centered care. To evaluate how AI mitigates biases, improves interpretability, and promotes inclusivity in dermatopathology while highlighting novel technologies like multimodal models and explainable AI (XAI).</p><h3>Results</h3><p dir="ltr">AI‐driven tools demonstrate significant improvements in diagnostic precision, particularly through multimodal models that integrate histological, genetic, and clinical data. Inclusive frameworks, such as the Monk scale, and advanced segmentation methods effectively address dataset biases. However, challenges such as the “black box” nature of AI, ethical concerns about data privacy, and limited access to advanced technologies in low‐resource settings remain.</p><h3>Conclusion</h3><p dir="ltr">AI offers transformative potential in dermatopathology, enabling equitable, and innovative diagnostics. Overcoming persistent challenges will require collaboration among dermatopathologists, AI developers, and policymakers. By prioritizing inclusivity, transparency, and interdisciplinary efforts, AI can redefine global standards in dermatopathology and foster patient‐centered care.</p><h2>Other Information</h2><p dir="ltr">Published in: Dermatological Reviews<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/der2.70018" target="_blank">https://dx.doi.org/10.1002/der2.70018</a></p>
eu_rights_str_mv openAccess
id Manara2_000705a62041d212a13f82ae4f9eb496
identifier_str_mv 10.1002/der2.70018
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/30234127
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
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rights_invalid_str_mv CC BY 4.0
spelling Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future DiagnosticsDiala Ra'Ed Kamal Kakish (22330627)Jehad Feras AlSamhori (17746809)Andy Noel Ramirez Fajardo (22330630)Lana N. Qaqish (22330633)Layan Ahmed Jaber (22330636)Rawan Abujudeh (22330639)Mohammad Hathal Mahmoud Al‐Zuriqat (22330642)Amina Yahya Mohammed (22330645)Abdulqadir J. Nashwan (11659453)Health sciencesHealth services and systemsPhilosophy and religious studiesApplied ethicsartificial Intelligence in dermatopathologydiagnostic biasexplainable AI (XAI)multimodal diagnosticsprecision medicine<h3>Background</h3><p dir="ltr">Artificial intelligence (AI) is transforming dermatopathology by enhancing diagnostic accuracy, efficiency, and precision medicine. Despite its promise, challenges such as dataset biases, underrepresentation of diverse populations, and limited transparency hinder its widespread adoption. Addressing these gaps can set a new standard for equitable and patient‐centered care. To evaluate how AI mitigates biases, improves interpretability, and promotes inclusivity in dermatopathology while highlighting novel technologies like multimodal models and explainable AI (XAI).</p><h3>Results</h3><p dir="ltr">AI‐driven tools demonstrate significant improvements in diagnostic precision, particularly through multimodal models that integrate histological, genetic, and clinical data. Inclusive frameworks, such as the Monk scale, and advanced segmentation methods effectively address dataset biases. However, challenges such as the “black box” nature of AI, ethical concerns about data privacy, and limited access to advanced technologies in low‐resource settings remain.</p><h3>Conclusion</h3><p dir="ltr">AI offers transformative potential in dermatopathology, enabling equitable, and innovative diagnostics. Overcoming persistent challenges will require collaboration among dermatopathologists, AI developers, and policymakers. By prioritizing inclusivity, transparency, and interdisciplinary efforts, AI can redefine global standards in dermatopathology and foster patient‐centered care.</p><h2>Other Information</h2><p dir="ltr">Published in: Dermatological Reviews<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/der2.70018" target="_blank">https://dx.doi.org/10.1002/der2.70018</a></p>2025-01-17T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1002/der2.70018https://figshare.com/articles/journal_contribution/Transforming_Dermatopathology_With_AI_Addressing_Bias_Enhancing_Interpretability_and_Shaping_Future_Diagnostics/30234127CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/302341272025-01-17T09:00:00Z
spellingShingle Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future Diagnostics
Diala Ra'Ed Kamal Kakish (22330627)
Health sciences
Health services and systems
Philosophy and religious studies
Applied ethics
artificial Intelligence in dermatopathology
diagnostic bias
explainable AI (XAI)
multimodal diagnostics
precision medicine
status_str publishedVersion
title Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future Diagnostics
title_full Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future Diagnostics
title_fullStr Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future Diagnostics
title_full_unstemmed Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future Diagnostics
title_short Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future Diagnostics
title_sort Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future Diagnostics
topic Health sciences
Health services and systems
Philosophy and religious studies
Applied ethics
artificial Intelligence in dermatopathology
diagnostic bias
explainable AI (XAI)
multimodal diagnostics
precision medicine