Integrated transcriptional‐phenotypic analysis captures systemic immunomodulation following antiangiogenic therapy in renal cell carcinoma patients

Integrated transcriptional‐phenotypic analysis captures systemic immunomodulation following antiangiogenic therapy in renal cell carcinoma patients

<h3>Background</h3><p dir="ltr">The combination of immune checkpoint blockade (ICB) with standard therapies is becoming a common approach for overcoming resistance to cancer immunotherapy in most human malignancies including metastatic renal cell carcinoma (mRCC). In this...

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Main Author: Darawan Rinchai (742366) (author)
Other Authors: Elena Verzoni (725945) (author), Veronica Huber (264942) (author), Agata Cova (8568057) (author), Paola Squarcina (8568060) (author), Loris De Cecco (107073) (author), Filippo Braud (6424019) (author), Raffaele Ratta (14778157) (author), Matteo Dugo (136516) (author), Luca Lalli (9412753) (author), Viviana Vallacchi (7872872) (author), Monica Rodolfo (370777) (author), Jessica Roelands (7516439) (author), Chiara Castelli (5863631) (author), Damien Chaussabel (26369) (author), Giuseppe Procopio (503244) (author), Davide Bedognetti (9471254) (author), Licia Rivoltini (264945) (author)
Published: 2021
Subjects:
Biological sciences
Bioinformatics and computational biology
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Immunology
Oncology and carcinogenesis
antiangiogenics
bioinformatics
blood transcriptomic profile
cancer biomarkers
immunomonitoring
immunosuppression
immunotherapy
myeloid-derived suppressor cells
pazopanib
renal cell carcinoma
transcriptional modular repertoire analysis
tyrosine kinase inhibitors
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