DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer

DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer

<h3>Background</h3><p dir="ltr">High expression of immune checkpoints in tumor microenvironment plays significant roles in inhibiting anti-tumor immunity, which is associated with poor prognosis and cancer progression. Major epigenetic modifications in both DNA and histon...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Varun Sasidharan Nair (5396393) (author)
مؤلفون آخرون:	Haytham El Salhat (5396387) (author), Rowaida Z. Taha (8854754) (author), Anne John (341927) (author), Bassam R. Ali (8711034) (author), Eyad Elkord (5396390) (author)
منشور في:	2018
الموضوعات:	Biomedical and clinical sciences Oncology and carcinogenesis Breast cancer Immune checkpoints PD-L1 DNA methylation Histone trimethylation
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة

DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer
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