Coevolving residues distant from the ligand binding site are involved in GAF domain function
<p dir="ltr">Ligand binding to GAF domains regulates the activity of associated catalytic domains in various proteins, such as the cGMP-hydrolyzing catalytic domain of phosphodiesterase 5 (PDE5) activated by cGMP binding to GAFa domain. However, the specific residues involved and the...
محفوظ في:
| المؤلف الرئيسي: | Wesam S. Ahmed (10170053) (author) |
|---|---|
| مؤلفون آخرون: | Anupriya M. Geethakumari (17052375) (author), Asfia Sultana (19170880) (author), Anmol Tiwari (22393294) (author), Tausif Altamash (3846304) (author), Najla Arshad (19438042) (author), Sandhya S. Visweswariah (10736916) (author), Kabir H. Biswas (5705864) (author) |
| منشور في: |
2025
|
| الموضوعات: | |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
مواد مشابهة
-
Phosphodiesterase 5 (PDE5): Structure-function regulation and therapeutic applications of inhibitors
حسب: Wesam S. Ahmed (10170053)
منشور في: (2021) -
Efficacy and safety of ensifentrine, a novel phosphodiesterase 3 and 4 inhibitor, in chronic obstructive pulmonary disease: A systematic review and meta-analysis
حسب: Eeshal Fatima (18255772)
منشور في: (2024) -
COUSCOus: improved protein contact prediction using an empirical Bayes covariance estimator
حسب: Reda Rawi (391865)
منشور في: (2016) -
Exploring the Dynamic Interplay of Deleterious Variants on the RAF1–RAP1A Binding in Cancer: Conformational Analysis, Binding Free Energy, and Essential Dynamics
حسب: Abbas Khan (5141000)
منشور في: (2024) -
The Impact of Industry 5.0 Technologies on the Performance within the Healthcare Sector through the Integration of Gamification-Based Learning Programs
حسب: Alsuwaidi, Laila
منشور في: (2023)