Unexplained massive pulmonary embolism in acromegaly patient: A case report
<h3>Key Clinical Message</h3><p dir="ltr">Our case highlights the importance of recognizing acromegaly as a potential risk factor for venous thromboembolism (VTE). Despite a thorough thrombophilia workup yielding unremarkable results, further research is warranted to eluc...
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2024
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| _version_ | 1864513542639583232 |
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| author | Usamah Al‐Anbagi (14778037) |
| author2 | Shybin Usman (14778040) Abdulrahman Saad (21841940) Abdulqadir J. Nashwan (11659453) |
| author2_role | author author author |
| author_facet | Usamah Al‐Anbagi (14778037) Shybin Usman (14778040) Abdulrahman Saad (21841940) Abdulqadir J. Nashwan (11659453) |
| author_role | author |
| dc.creator.none.fl_str_mv | Usamah Al‐Anbagi (14778037) Shybin Usman (14778040) Abdulrahman Saad (21841940) Abdulqadir J. Nashwan (11659453) |
| dc.date.none.fl_str_mv | 2024-05-10T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1002/ccr3.8867 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Unexplained_massive_pulmonary_embolism_in_acromegaly_patient_A_case_report/29715467 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Medical biochemistry and metabolomics acromegaly anticoagulation growth hormone hypercoagulability pulmonary embolism thrombophilia screening |
| dc.title.none.fl_str_mv | Unexplained massive pulmonary embolism in acromegaly patient: A case report |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Key Clinical Message</h3><p dir="ltr">Our case highlights the importance of recognizing acromegaly as a potential risk factor for venous thromboembolism (VTE). Despite a thorough thrombophilia workup yielding unremarkable results, further research is warranted to elucidate the underlying mechanisms linking acromegaly and thrombophilia. This understanding will aid in improving risk assessment and management strategies for patients with acromegaly.</p><p dir="ltr">Acromegaly, a rare disorder characterized by excessive growth hormone secretion, is associated with various comorbidities including hypertension, diabetes mellitus, and obstructive sleep apnea. While previous studies have identified abnormalities in hemostatic factors in acromegaly patients, the association between acromegaly and venous thromboembolism (VTE) remains poorly understood. We present the case of a 36‐year‐old male with a history of acromegaly who presented with acute dyspnea, chest pain, and cough. Despite a prior trans‐sphenoidal hypophysectomy, his acromegaly symptoms persisted. Upon evaluation, he was found to have bilateral pulmonary embolism. Thorough thrombophilia workup was unremarkable, suggesting acromegaly as a potential risk factor for VTE.</p><h2>Other Information</h2><p dir="ltr">Published in: Clinical Case Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/ccr3.8867" target="_blank">https://dx.doi.org/10.1002/ccr3.8867</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_049605b7b4eacbf7f1dc871353ac1428 |
| identifier_str_mv | 10.1002/ccr3.8867 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29715467 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Unexplained massive pulmonary embolism in acromegaly patient: A case reportUsamah Al‐Anbagi (14778037)Shybin Usman (14778040)Abdulrahman Saad (21841940)Abdulqadir J. Nashwan (11659453)Biomedical and clinical sciencesCardiovascular medicine and haematologyClinical sciencesMedical biochemistry and metabolomicsacromegalyanticoagulationgrowth hormonehypercoagulabilitypulmonary embolismthrombophilia screening<h3>Key Clinical Message</h3><p dir="ltr">Our case highlights the importance of recognizing acromegaly as a potential risk factor for venous thromboembolism (VTE). Despite a thorough thrombophilia workup yielding unremarkable results, further research is warranted to elucidate the underlying mechanisms linking acromegaly and thrombophilia. This understanding will aid in improving risk assessment and management strategies for patients with acromegaly.</p><p dir="ltr">Acromegaly, a rare disorder characterized by excessive growth hormone secretion, is associated with various comorbidities including hypertension, diabetes mellitus, and obstructive sleep apnea. While previous studies have identified abnormalities in hemostatic factors in acromegaly patients, the association between acromegaly and venous thromboembolism (VTE) remains poorly understood. We present the case of a 36‐year‐old male with a history of acromegaly who presented with acute dyspnea, chest pain, and cough. Despite a prior trans‐sphenoidal hypophysectomy, his acromegaly symptoms persisted. Upon evaluation, he was found to have bilateral pulmonary embolism. Thorough thrombophilia workup was unremarkable, suggesting acromegaly as a potential risk factor for VTE.</p><h2>Other Information</h2><p dir="ltr">Published in: Clinical Case Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/ccr3.8867" target="_blank">https://dx.doi.org/10.1002/ccr3.8867</a></p>2024-05-10T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1002/ccr3.8867https://figshare.com/articles/journal_contribution/Unexplained_massive_pulmonary_embolism_in_acromegaly_patient_A_case_report/29715467CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/297154672024-05-10T09:00:00Z |
| spellingShingle | Unexplained massive pulmonary embolism in acromegaly patient: A case report Usamah Al‐Anbagi (14778037) Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Medical biochemistry and metabolomics acromegaly anticoagulation growth hormone hypercoagulability pulmonary embolism thrombophilia screening |
| status_str | publishedVersion |
| title | Unexplained massive pulmonary embolism in acromegaly patient: A case report |
| title_full | Unexplained massive pulmonary embolism in acromegaly patient: A case report |
| title_fullStr | Unexplained massive pulmonary embolism in acromegaly patient: A case report |
| title_full_unstemmed | Unexplained massive pulmonary embolism in acromegaly patient: A case report |
| title_short | Unexplained massive pulmonary embolism in acromegaly patient: A case report |
| title_sort | Unexplained massive pulmonary embolism in acromegaly patient: A case report |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Medical biochemistry and metabolomics acromegaly anticoagulation growth hormone hypercoagulability pulmonary embolism thrombophilia screening |