Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper

<p dir="ltr">Simple, portable, and low-cost paper-based sensors are alternative devices that have the potential to replace high-cost sensing technologies. The compatibility of the paper base biosensors for both chemical and biochemical accentuates its feasibility for application in c...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Mithra Geetha (14151807) (author)
مؤلفون آخرون: Kishor Kumar Sadasivuni (8036039) (author), Maryam Al-Ejji (5244842) (author), Nandagopal Sivadas (17714322) (author), Bagmita Bhattacharyya (17714298) (author), Farzana N. Musthafa (17714325) (author), Sarya Alfarwati (17714328) (author), Tamanna Jannat Promi (17714331) (author), Sumayya Ali Ahmad (17714334) (author), Sara Alabed (17714337) (author), Dima Anwar Hijazi (17714340) (author), Fatimatulzahraa Alsaedi (17317060) (author), Faozia Nasser Al-Shaibah (17714343) (author)
منشور في: 2023
الموضوعات:
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_version_ 1864513534238392320
author Mithra Geetha (14151807)
author2 Kishor Kumar Sadasivuni (8036039)
Maryam Al-Ejji (5244842)
Nandagopal Sivadas (17714322)
Bagmita Bhattacharyya (17714298)
Farzana N. Musthafa (17714325)
Sarya Alfarwati (17714328)
Tamanna Jannat Promi (17714331)
Sumayya Ali Ahmad (17714334)
Sara Alabed (17714337)
Dima Anwar Hijazi (17714340)
Fatimatulzahraa Alsaedi (17317060)
Faozia Nasser Al-Shaibah (17714343)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author_facet Mithra Geetha (14151807)
Kishor Kumar Sadasivuni (8036039)
Maryam Al-Ejji (5244842)
Nandagopal Sivadas (17714322)
Bagmita Bhattacharyya (17714298)
Farzana N. Musthafa (17714325)
Sarya Alfarwati (17714328)
Tamanna Jannat Promi (17714331)
Sumayya Ali Ahmad (17714334)
Sara Alabed (17714337)
Dima Anwar Hijazi (17714340)
Fatimatulzahraa Alsaedi (17317060)
Faozia Nasser Al-Shaibah (17714343)
author_role author
dc.creator.none.fl_str_mv Mithra Geetha (14151807)
Kishor Kumar Sadasivuni (8036039)
Maryam Al-Ejji (5244842)
Nandagopal Sivadas (17714322)
Bagmita Bhattacharyya (17714298)
Farzana N. Musthafa (17714325)
Sarya Alfarwati (17714328)
Tamanna Jannat Promi (17714331)
Sumayya Ali Ahmad (17714334)
Sara Alabed (17714337)
Dima Anwar Hijazi (17714340)
Fatimatulzahraa Alsaedi (17317060)
Faozia Nasser Al-Shaibah (17714343)
dc.date.none.fl_str_mv 2023-04-10T03:00:00Z
dc.identifier.none.fl_str_mv 10.1007/s10895-023-03220-4
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Design_and_Development_of_Inexpensive_Paper-Based_Chemosensors_for_Detection_of_Divalent_Copper/24921405
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Chemical sciences
Analytical chemistry
Engineering
Chemical engineering
Sensor
Monitoring
Dye system
Copper
dc.title.none.fl_str_mv Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">Simple, portable, and low-cost paper-based sensors are alternative devices that have the potential to replace high-cost sensing technologies. The compatibility of the paper base biosensors for both chemical and biochemical accentuates its feasibility for application in clinical diagnosis, environmental monitoring, and food quality monitoring. High concentration of copper in blood serum and urine is associated with diseases like liver diseases, carcinomas, acute and chronic infections, rheumatoid arthritis, etc. Detection of copper concentration can give an early sign of Alzheimer disease. Apart from that genetic Wilson's disease can be detected by evaluating the concentration of copper in the urine. In view of the above advantages, a novel and the highly sensitive paper-based sensor has been designed for the selective detection of Cu<sup>2+</sup> ions. The fast and highly sensitive chemiresistive multi-dye system sensor can detect Cu<sup>2+</sup> ions selectively in as low as 2.23 ppm concentration. Least interference has been observed for counter ion in the detection of Cu<sup>2+</sup>. Copper chloride, nitrate, and acetate were used to validate the detection process. This assay provides a very high selectivity of Cu<sup>2+</sup> ion over other metal cations such as Na<sup>+</sup>, Mg<sup>2+</sup>, Ca2<sup>+</sup>, etc. The easy preparation and high stability of dye solutions, easy functionalization of the paper-based sensors, high selectivity over other cations, low interference of counter anion, and significantly low detection limit of 2.23 ppm make it an effective Cu<sup>2+</sup> ion sensor for real-time application in near future.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Fluorescence<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10895-023-03220-4" target="_blank">https://dx.doi.org/10.1007/s10895-023-03220-4</a></p>
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network_acronym_str Manara2
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spelling Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent CopperMithra Geetha (14151807)Kishor Kumar Sadasivuni (8036039)Maryam Al-Ejji (5244842)Nandagopal Sivadas (17714322)Bagmita Bhattacharyya (17714298)Farzana N. Musthafa (17714325)Sarya Alfarwati (17714328)Tamanna Jannat Promi (17714331)Sumayya Ali Ahmad (17714334)Sara Alabed (17714337)Dima Anwar Hijazi (17714340)Fatimatulzahraa Alsaedi (17317060)Faozia Nasser Al-Shaibah (17714343)Chemical sciencesAnalytical chemistryEngineeringChemical engineeringSensorMonitoringDye systemCopper<p dir="ltr">Simple, portable, and low-cost paper-based sensors are alternative devices that have the potential to replace high-cost sensing technologies. The compatibility of the paper base biosensors for both chemical and biochemical accentuates its feasibility for application in clinical diagnosis, environmental monitoring, and food quality monitoring. High concentration of copper in blood serum and urine is associated with diseases like liver diseases, carcinomas, acute and chronic infections, rheumatoid arthritis, etc. Detection of copper concentration can give an early sign of Alzheimer disease. Apart from that genetic Wilson's disease can be detected by evaluating the concentration of copper in the urine. In view of the above advantages, a novel and the highly sensitive paper-based sensor has been designed for the selective detection of Cu<sup>2+</sup> ions. The fast and highly sensitive chemiresistive multi-dye system sensor can detect Cu<sup>2+</sup> ions selectively in as low as 2.23 ppm concentration. Least interference has been observed for counter ion in the detection of Cu<sup>2+</sup>. Copper chloride, nitrate, and acetate were used to validate the detection process. This assay provides a very high selectivity of Cu<sup>2+</sup> ion over other metal cations such as Na<sup>+</sup>, Mg<sup>2+</sup>, Ca2<sup>+</sup>, etc. The easy preparation and high stability of dye solutions, easy functionalization of the paper-based sensors, high selectivity over other cations, low interference of counter anion, and significantly low detection limit of 2.23 ppm make it an effective Cu<sup>2+</sup> ion sensor for real-time application in near future.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Fluorescence<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10895-023-03220-4" target="_blank">https://dx.doi.org/10.1007/s10895-023-03220-4</a></p>2023-04-10T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s10895-023-03220-4https://figshare.com/articles/journal_contribution/Design_and_Development_of_Inexpensive_Paper-Based_Chemosensors_for_Detection_of_Divalent_Copper/24921405CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/249214052023-04-10T03:00:00Z
spellingShingle Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper
Mithra Geetha (14151807)
Chemical sciences
Analytical chemistry
Engineering
Chemical engineering
Sensor
Monitoring
Dye system
Copper
status_str publishedVersion
title Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper
title_full Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper
title_fullStr Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper
title_full_unstemmed Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper
title_short Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper
title_sort Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper
topic Chemical sciences
Analytical chemistry
Engineering
Chemical engineering
Sensor
Monitoring
Dye system
Copper