MicroRNA-24-3p Targets Notch and Other Vascular Morphogens to Regulate Post-ischemic Microvascular Responses in Limb Muscles

MicroRNA-24-3p Targets Notch and Other Vascular Morphogens to Regulate Post-ischemic Microvascular Responses in Limb Muscles

<p dir="ltr">MicroRNAs (miRs) regulate complex processes, including angiogenesis, by targeting multiple mRNAs. miR-24-3p-3p directly represses eNOS, GATA2, and PAK4 in endothelial cells (ECs), thus inhibiting angiogenesis during development and in the infarcted heart. miR-24-3p is wi...

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Bibliographic Details
Main Author: Micol Marchetti (18623410) (author)
Other Authors: Marco Meloni (7714451) (author), Maryam Anwar (6458852) (author), Ayman Al-Haj-Zen (18623413) (author), Graciela Sala-Newby (18623416) (author), Sadie Slater (18623419) (author), Kerrie Ford (18623422) (author), Andrea Caporali (7714448) (author), Costanza Emanueli (299596) (author)
Published: 2020
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Cardiovascular medicine and haematology
miR-24-3p
angiogenesis
endothelial cells
Notch
β-catenin
limb ischemia
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