Shock index in patients with traumatic solid organ injury as a predictor of massive blood transfusion protocol activation
<h3>Purpose</h3><p dir="ltr">We aimed to assess the utility of shock index (SI) to predict the need for massive transfusion protocol (MTP) in patients with solid organ injury (SOI) in a Level 1 Trauma center.</p><h3>Methods</h3><p dir="ltr"&...
محفوظ في:
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| مؤلفون آخرون: | , , , , |
| منشور في: |
2019
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إضافة وسم
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| _version_ | 1864513566551310336 |
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| author | Ayman El-Menyar (440103) |
| author2 | Gaby Jabbour (4578832) Mohammad Asim (178880) Husham Abdelrahman (768893) Ismail Mahmood (14150352) Hassan Al-Thani (440106) |
| author2_role | author author author author author |
| author_facet | Ayman El-Menyar (440103) Gaby Jabbour (4578832) Mohammad Asim (178880) Husham Abdelrahman (768893) Ismail Mahmood (14150352) Hassan Al-Thani (440106) |
| author_role | author |
| dc.creator.none.fl_str_mv | Ayman El-Menyar (440103) Gaby Jabbour (4578832) Mohammad Asim (178880) Husham Abdelrahman (768893) Ismail Mahmood (14150352) Hassan Al-Thani (440106) |
| dc.date.none.fl_str_mv | 2019-10-07T21:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1186/s40621-019-0218-7 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Shock_index_in_patients_with_traumatic_solid_organ_injury_as_a_predictor_of_massive_blood_transfusion_protocol_activation/21598518 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Shock index Solid organ injury Blood transfusion Laparotomy MTP Trauma |
| dc.title.none.fl_str_mv | Shock index in patients with traumatic solid organ injury as a predictor of massive blood transfusion protocol activation |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Purpose</h3><p dir="ltr">We aimed to assess the utility of shock index (SI) to predict the need for massive transfusion protocol (MTP) in patients with solid organ injury (SOI) in a Level 1 Trauma center.</p><h3>Methods</h3><p dir="ltr">We conducted a retrospective analysis for patients with SOI between 2011 and 2014. Patients were categorized according to on-admission SI into low (< 0.8) and high SI (≥0.8) group.</p><h3>Results</h3><p dir="ltr">A total of 4500 patients were admitted with trauma, of them 572 sustained SOIs (289 patients had SI ≥0.8). In comparison to low SI, patients with high SI were younger, had higher injury severity scores (ISS) and lower Trauma and Injury Severity Score (TRISS); (<i>p</i>< 0.001). The proportion of exploratory laparotomy (EXLap), blood transfusion (BT), MTP activation, sepsis and hospital mortality were significantly higher in patients with high SI. Serum lactate (<i>r</i>= 0.34), hematocrit (<i>r</i>= − 0.34), ABC score (<i>r</i>= 0.62), ISS (<i>r</i>= 0.35), and amount of transfused blood (<i>r</i>= 0.22) were significantly correlated with SI. On multivariable regression analysis using 9 relevant variables (age, sex, ISS, ED GCS, serum lactate, hematocrit, Abdomen AIS and Focused assessment with sonography in trauma (FAST) and SI), SI ≥ 0.8 was an independent predictor of BT (OR 2.80; 95%CI 1.56–4.95) and MTP (OR 2.81;95% CI 1.09–7.21) .</p><h3>Conclusions</h3><p dir="ltr">In patients with SOI, SI is a simple bedside predictor for BT and MTP activation. Further prospective studies are needed to support our findings.</p><h2>Other Information</h2><p dir="ltr">Published in: Injury Epidemiology<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1186/s40621-019-0218-7" target="_blank">http://dx.doi.org/10.1186/s40621-019-0218-7</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_063f4f943aaafa576cfbd1e4c1030365 |
| identifier_str_mv | 10.1186/s40621-019-0218-7 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/21598518 |
| publishDate | 2019 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Shock index in patients with traumatic solid organ injury as a predictor of massive blood transfusion protocol activationAyman El-Menyar (440103)Gaby Jabbour (4578832)Mohammad Asim (178880)Husham Abdelrahman (768893)Ismail Mahmood (14150352)Hassan Al-Thani (440106)Biomedical and clinical sciencesClinical sciencesShock indexSolid organ injuryBlood transfusionLaparotomyMTPTrauma<h3>Purpose</h3><p dir="ltr">We aimed to assess the utility of shock index (SI) to predict the need for massive transfusion protocol (MTP) in patients with solid organ injury (SOI) in a Level 1 Trauma center.</p><h3>Methods</h3><p dir="ltr">We conducted a retrospective analysis for patients with SOI between 2011 and 2014. Patients were categorized according to on-admission SI into low (< 0.8) and high SI (≥0.8) group.</p><h3>Results</h3><p dir="ltr">A total of 4500 patients were admitted with trauma, of them 572 sustained SOIs (289 patients had SI ≥0.8). In comparison to low SI, patients with high SI were younger, had higher injury severity scores (ISS) and lower Trauma and Injury Severity Score (TRISS); (<i>p</i>< 0.001). The proportion of exploratory laparotomy (EXLap), blood transfusion (BT), MTP activation, sepsis and hospital mortality were significantly higher in patients with high SI. Serum lactate (<i>r</i>= 0.34), hematocrit (<i>r</i>= − 0.34), ABC score (<i>r</i>= 0.62), ISS (<i>r</i>= 0.35), and amount of transfused blood (<i>r</i>= 0.22) were significantly correlated with SI. On multivariable regression analysis using 9 relevant variables (age, sex, ISS, ED GCS, serum lactate, hematocrit, Abdomen AIS and Focused assessment with sonography in trauma (FAST) and SI), SI ≥ 0.8 was an independent predictor of BT (OR 2.80; 95%CI 1.56–4.95) and MTP (OR 2.81;95% CI 1.09–7.21) .</p><h3>Conclusions</h3><p dir="ltr">In patients with SOI, SI is a simple bedside predictor for BT and MTP activation. Further prospective studies are needed to support our findings.</p><h2>Other Information</h2><p dir="ltr">Published in: Injury Epidemiology<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1186/s40621-019-0218-7" target="_blank">http://dx.doi.org/10.1186/s40621-019-0218-7</a></p>2019-10-07T21:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1186/s40621-019-0218-7https://figshare.com/articles/journal_contribution/Shock_index_in_patients_with_traumatic_solid_organ_injury_as_a_predictor_of_massive_blood_transfusion_protocol_activation/21598518CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/215985182019-10-07T21:00:00Z |
| spellingShingle | Shock index in patients with traumatic solid organ injury as a predictor of massive blood transfusion protocol activation Ayman El-Menyar (440103) Biomedical and clinical sciences Clinical sciences Shock index Solid organ injury Blood transfusion Laparotomy MTP Trauma |
| status_str | publishedVersion |
| title | Shock index in patients with traumatic solid organ injury as a predictor of massive blood transfusion protocol activation |
| title_full | Shock index in patients with traumatic solid organ injury as a predictor of massive blood transfusion protocol activation |
| title_fullStr | Shock index in patients with traumatic solid organ injury as a predictor of massive blood transfusion protocol activation |
| title_full_unstemmed | Shock index in patients with traumatic solid organ injury as a predictor of massive blood transfusion protocol activation |
| title_short | Shock index in patients with traumatic solid organ injury as a predictor of massive blood transfusion protocol activation |
| title_sort | Shock index in patients with traumatic solid organ injury as a predictor of massive blood transfusion protocol activation |
| topic | Biomedical and clinical sciences Clinical sciences Shock index Solid organ injury Blood transfusion Laparotomy MTP Trauma |