Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study

<p dir="ltr">An increasing number of systematic reviews and meta-analyses (SRMAs) have been published in the field of sleep medicine. We evaluated the methodological issues of these SRMAs. A protocol was developed in advance. Three databases were searched from inception to October 20...

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Main Author: Chang Xu (102022) (author)
Other Authors: Luis Furuya-Kanamori (477124) (author), Joey S.W. Kwong (16932546) (author), Sheng Li (107261) (author), Yu Liu (6938) (author), Suhail A. Doi (9552474) (author)
Published: 2021
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author Chang Xu (102022)
author2 Luis Furuya-Kanamori (477124)
Joey S.W. Kwong (16932546)
Sheng Li (107261)
Yu Liu (6938)
Suhail A. Doi (9552474)
author2_role author
author
author
author
author
author_facet Chang Xu (102022)
Luis Furuya-Kanamori (477124)
Joey S.W. Kwong (16932546)
Sheng Li (107261)
Yu Liu (6938)
Suhail A. Doi (9552474)
author_role author
dc.creator.none.fl_str_mv Chang Xu (102022)
Luis Furuya-Kanamori (477124)
Joey S.W. Kwong (16932546)
Sheng Li (107261)
Yu Liu (6938)
Suhail A. Doi (9552474)
dc.date.none.fl_str_mv 2021-06-01T00:00:00Z
dc.identifier.none.fl_str_mv 10.1016/j.smrv.2021.101434
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Methodological_issues_of_systematic_reviews_and_meta-analyses_in_the_field_of_sleep_medicine_A_meta-epidemiological_study/24083700
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
Mathematical sciences
Statistics
Evidence-based decision
Systematic reviews
Meta-analysis
Methodology validity
Meta-epidemiological study
dc.title.none.fl_str_mv Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">An increasing number of systematic reviews and meta-analyses (SRMAs) have been published in the field of sleep medicine. We evaluated the methodological issues of these SRMAs. A protocol was developed in advance. Three databases were searched from inception to October 2019 for SRMAs published in major academic journals of sleep medicine that assessed healthcare interventions. The AMSTAR 2.0 instrument was used to evaluate the methodological issues and a multivariable regression analysis was conducted to investigate potential measures associated with methodological validity. We identified 163 SRMAs. The median number of missing safeguards of these SRMAs was 7 out of 16 (Interquartile range, IQR: 6–9), and on average, two of these missing safeguards were critical weaknesses. Our regression analysis suggested that SRMAs published in recent years (β = 0.16; 95%CI: 0.08, 0.24; p = 0.002), with the first author from Europe (β = 0.08; 95%CI: 0.02, 0.14; p = 0.013) tend to have higher relative methodological ranks. In conclusion, the methodological validity for current SRMAs in sleep medicine was poor. Further efforts to improve the methodological validity are needed.</p><h2>Other Information</h2><p dir="ltr">Published in: Sleep Medicine Reviews<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.smrv.2021.101434" target="_blank">https://dx.doi.org/10.1016/j.smrv.2021.101434</a></p>
eu_rights_str_mv openAccess
id Manara2_07a43181bc15fbfd17909990713bc270
identifier_str_mv 10.1016/j.smrv.2021.101434
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/24083700
publishDate 2021
repository.mail.fl_str_mv
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rights_invalid_str_mv CC BY 4.0
spelling Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological studyChang Xu (102022)Luis Furuya-Kanamori (477124)Joey S.W. Kwong (16932546)Sheng Li (107261)Yu Liu (6938)Suhail A. Doi (9552474)Biomedical and clinical sciencesPharmacology and pharmaceutical sciencesMathematical sciencesStatisticsEvidence-based decisionSystematic reviewsMeta-analysisMethodology validityMeta-epidemiological study<p dir="ltr">An increasing number of systematic reviews and meta-analyses (SRMAs) have been published in the field of sleep medicine. We evaluated the methodological issues of these SRMAs. A protocol was developed in advance. Three databases were searched from inception to October 2019 for SRMAs published in major academic journals of sleep medicine that assessed healthcare interventions. The AMSTAR 2.0 instrument was used to evaluate the methodological issues and a multivariable regression analysis was conducted to investigate potential measures associated with methodological validity. We identified 163 SRMAs. The median number of missing safeguards of these SRMAs was 7 out of 16 (Interquartile range, IQR: 6–9), and on average, two of these missing safeguards were critical weaknesses. Our regression analysis suggested that SRMAs published in recent years (β = 0.16; 95%CI: 0.08, 0.24; p = 0.002), with the first author from Europe (β = 0.08; 95%CI: 0.02, 0.14; p = 0.013) tend to have higher relative methodological ranks. In conclusion, the methodological validity for current SRMAs in sleep medicine was poor. Further efforts to improve the methodological validity are needed.</p><h2>Other Information</h2><p dir="ltr">Published in: Sleep Medicine Reviews<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.smrv.2021.101434" target="_blank">https://dx.doi.org/10.1016/j.smrv.2021.101434</a></p>2021-06-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.smrv.2021.101434https://figshare.com/articles/journal_contribution/Methodological_issues_of_systematic_reviews_and_meta-analyses_in_the_field_of_sleep_medicine_A_meta-epidemiological_study/24083700CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/240837002021-06-01T00:00:00Z
spellingShingle Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
Chang Xu (102022)
Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
Mathematical sciences
Statistics
Evidence-based decision
Systematic reviews
Meta-analysis
Methodology validity
Meta-epidemiological study
status_str publishedVersion
title Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
title_full Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
title_fullStr Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
title_full_unstemmed Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
title_short Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
title_sort Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
topic Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
Mathematical sciences
Statistics
Evidence-based decision
Systematic reviews
Meta-analysis
Methodology validity
Meta-epidemiological study