Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications

Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications

<p>Loss of function mutations in store-operated Ca<sup>2+</sup> entry (SOCE) are associated with severe paediatric disorders in humans, including combined immunodeficiency, anaemia, thrombocytopenia, anhidrosis and muscle hypotonia. Given its central role in immune cell activation,...

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Bibliographic Details
Main Author: Fang Yu (156838) (author)
Other Authors: Raphael Courjaret (9592368) (author), Asha Elmi (9592371) (author), Ethel Alcantara Adap (14779645) (author), Nelson N. Orie (14779648) (author), Fawzi Zghyer (14779651) (author), Satanay Hubrack (194364) (author), Sajad Hayat (14779654) (author), Nidal Asaad (284935) (author), Stefan Worgall (364238) (author), Manikkam Suthanthiran (713590) (author), Vidya Mohamed Ali (14779657) (author), Khaled Machaca (194372) (author)
Published: 2022
Subjects:
Biomedical and clinical sciences
Medical physiology
Immunoreceptors
Muscle Hypotonia
Inflammatory Diseases
Thrombocytopenia
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