Nano-vitamin C: A promising candidate for therapeutic applications
<p dir="ltr">Vitamin C is an important nutrient implicated in different physiological functions in humans. Despite its important biological functions, therapeutic applications of vitamin C are rare and its use is further impacted by low chemical stability. Several nano-encapsulation...
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| مؤلفون آخرون: | , , , , , , |
| منشور في: |
2023
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إضافة وسم
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| _version_ | 1864513542555697152 |
|---|---|
| author | Takwa Bedhiafi (14153460) |
| author2 | Sourour Idoudi (14153457) Queenie Fernandes (14557388) Lobna Al-Zaidan (14557394) Shahab Uddin (154400) Said Dermime (79420) Nashiru Billa (4375261) Maysaloun Merhi (4246147) |
| author2_role | author author author author author author author |
| author_facet | Takwa Bedhiafi (14153460) Sourour Idoudi (14153457) Queenie Fernandes (14557388) Lobna Al-Zaidan (14557394) Shahab Uddin (154400) Said Dermime (79420) Nashiru Billa (4375261) Maysaloun Merhi (4246147) |
| author_role | author |
| dc.creator.none.fl_str_mv | Takwa Bedhiafi (14153460) Sourour Idoudi (14153457) Queenie Fernandes (14557388) Lobna Al-Zaidan (14557394) Shahab Uddin (154400) Said Dermime (79420) Nashiru Billa (4375261) Maysaloun Merhi (4246147) |
| dc.date.none.fl_str_mv | 2023-02-01T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.biopha.2022.114093 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Nano-vitamin_C_A_promising_candidate_for_therapeutic_applications/24501058 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Medical biotechnology Pharmacology and pharmaceutical sciences Vitamin C Nano-vitamin C Therapeutic Clinical Nanomedicine |
| dc.title.none.fl_str_mv | Nano-vitamin C: A promising candidate for therapeutic applications |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Vitamin C is an important nutrient implicated in different physiological functions in humans. Despite its important biological functions, therapeutic applications of vitamin C are rare and its use is further impacted by low chemical stability. Several nano-encapsulation techniques have been described in the literature and yet, there are only a handful of clinical investigations dedicated to unlocking the therapeutic applications of nano-encapsulated vitamin C. Clearly, further investigations are warranted in order to affirm the promising clinical potential of nano-encapsulated vitamin C. In this review, we describe the mechanisms of vitamin C activity as a modulator of crucial therapeutic uses in biological systems. We look at key factors affecting the chemical stability of vitamin C alone and in nano-encapsulated and explore pre-clinical and clinical evidence on current vitamin C nano-formulations along with their therapeutic applications. Finally, we critically appraise the gaps and opportunities prevailing in nano-vitamin C research and its potential translation towards relevant clinical outcomes.</p><h2>Other Information</h2><p dir="ltr">Published in: Biomedicine & Pharmacotherapy<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.biopha.2022.114093" target="_blank">https://dx.doi.org/10.1016/j.biopha.2022.114093</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_0a3d09d8888c2737c45c6d120759fc7d |
| identifier_str_mv | 10.1016/j.biopha.2022.114093 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/24501058 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Nano-vitamin C: A promising candidate for therapeutic applicationsTakwa Bedhiafi (14153460)Sourour Idoudi (14153457)Queenie Fernandes (14557388)Lobna Al-Zaidan (14557394)Shahab Uddin (154400)Said Dermime (79420)Nashiru Billa (4375261)Maysaloun Merhi (4246147)Biomedical and clinical sciencesClinical sciencesMedical biotechnologyPharmacology and pharmaceutical sciencesVitamin CNano-vitamin CTherapeuticClinicalNanomedicine<p dir="ltr">Vitamin C is an important nutrient implicated in different physiological functions in humans. Despite its important biological functions, therapeutic applications of vitamin C are rare and its use is further impacted by low chemical stability. Several nano-encapsulation techniques have been described in the literature and yet, there are only a handful of clinical investigations dedicated to unlocking the therapeutic applications of nano-encapsulated vitamin C. Clearly, further investigations are warranted in order to affirm the promising clinical potential of nano-encapsulated vitamin C. In this review, we describe the mechanisms of vitamin C activity as a modulator of crucial therapeutic uses in biological systems. We look at key factors affecting the chemical stability of vitamin C alone and in nano-encapsulated and explore pre-clinical and clinical evidence on current vitamin C nano-formulations along with their therapeutic applications. Finally, we critically appraise the gaps and opportunities prevailing in nano-vitamin C research and its potential translation towards relevant clinical outcomes.</p><h2>Other Information</h2><p dir="ltr">Published in: Biomedicine & Pharmacotherapy<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.biopha.2022.114093" target="_blank">https://dx.doi.org/10.1016/j.biopha.2022.114093</a></p>2023-02-01T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.biopha.2022.114093https://figshare.com/articles/journal_contribution/Nano-vitamin_C_A_promising_candidate_for_therapeutic_applications/24501058CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/245010582023-02-01T03:00:00Z |
| spellingShingle | Nano-vitamin C: A promising candidate for therapeutic applications Takwa Bedhiafi (14153460) Biomedical and clinical sciences Clinical sciences Medical biotechnology Pharmacology and pharmaceutical sciences Vitamin C Nano-vitamin C Therapeutic Clinical Nanomedicine |
| status_str | publishedVersion |
| title | Nano-vitamin C: A promising candidate for therapeutic applications |
| title_full | Nano-vitamin C: A promising candidate for therapeutic applications |
| title_fullStr | Nano-vitamin C: A promising candidate for therapeutic applications |
| title_full_unstemmed | Nano-vitamin C: A promising candidate for therapeutic applications |
| title_short | Nano-vitamin C: A promising candidate for therapeutic applications |
| title_sort | Nano-vitamin C: A promising candidate for therapeutic applications |
| topic | Biomedical and clinical sciences Clinical sciences Medical biotechnology Pharmacology and pharmaceutical sciences Vitamin C Nano-vitamin C Therapeutic Clinical Nanomedicine |