Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders
<p dir="ltr">Neurodevelopmental and psychiatric disorders, which currently lack effective treatment strategies (<a href="https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1239315/full#B1" target="_blank">Aishworiya et al...
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2023
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| _version_ | 1864513520735879168 |
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| author | Farhan Mohammad (256409) |
| author2 | Mohd. Farooq Shaikh (9530995) Yasir Ahmed Syed (8923712) Fadel Tissir (245153) |
| author2_role | author author author |
| author_facet | Farhan Mohammad (256409) Mohd. Farooq Shaikh (9530995) Yasir Ahmed Syed (8923712) Fadel Tissir (245153) |
| author_role | author |
| dc.creator.none.fl_str_mv | Farhan Mohammad (256409) Mohd. Farooq Shaikh (9530995) Yasir Ahmed Syed (8923712) Fadel Tissir (245153) |
| dc.date.none.fl_str_mv | 2023-06-29T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.3389/fnmol.2023.1239315 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Editorial_Advances_in_understanding_synaptic_function_and_its_dysfunction_in_neurological_disorders/26776519 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Neurosciences synaptic plasticity cognition neurological disorder animal models molecular mechanism |
| dc.title.none.fl_str_mv | Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Neurodevelopmental and psychiatric disorders, which currently lack effective treatment strategies (<a href="https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1239315/full#B1" target="_blank">Aishworiya et al., 2022</a>), pose a significant challenge to worldwide public health systems (<a href="https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1239315/full#B6" target="_blank">Kularatna et al., 2022</a>). One of the core clinical phenotype associated with these disabling disorders are cognitive deficits, which is likely due to molecular mechanisms that affect long-term changes in synaptic development, function and plasticity (<a href="https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1239315/full#B9" target="_blank">Parenti et al., 2020</a>). Understanding these mechanisms are the crucial first step for addressing cognitive impairments associated with these complex neurological conditions (<a href="https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1239315/full#B5" target="_blank">Kozubski et al., 2021</a>). Toward this purpose, our Research Topic focuses on the intricate aspects of brain cognitive functions, including the role of specific proteins, therapeutic interventions, modulation of neuronal circuits, and the impact of molecular mechanisms on cognitive impairments.</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Molecular Neuroscience<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fnmol.2023.1239315" target="_blank">https://dx.doi.org/10.3389/fnmol.2023.1239315</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_0a59ca91c5dcd6621edec9a5b3a7d15d |
| identifier_str_mv | 10.3389/fnmol.2023.1239315 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/26776519 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Editorial: Advances in understanding synaptic function and its dysfunction in neurological disordersFarhan Mohammad (256409)Mohd. Farooq Shaikh (9530995)Yasir Ahmed Syed (8923712)Fadel Tissir (245153)Biomedical and clinical sciencesClinical sciencesNeurosciencessynaptic plasticitycognitionneurological disorderanimal modelsmolecular mechanism<p dir="ltr">Neurodevelopmental and psychiatric disorders, which currently lack effective treatment strategies (<a href="https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1239315/full#B1" target="_blank">Aishworiya et al., 2022</a>), pose a significant challenge to worldwide public health systems (<a href="https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1239315/full#B6" target="_blank">Kularatna et al., 2022</a>). One of the core clinical phenotype associated with these disabling disorders are cognitive deficits, which is likely due to molecular mechanisms that affect long-term changes in synaptic development, function and plasticity (<a href="https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1239315/full#B9" target="_blank">Parenti et al., 2020</a>). Understanding these mechanisms are the crucial first step for addressing cognitive impairments associated with these complex neurological conditions (<a href="https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1239315/full#B5" target="_blank">Kozubski et al., 2021</a>). Toward this purpose, our Research Topic focuses on the intricate aspects of brain cognitive functions, including the role of specific proteins, therapeutic interventions, modulation of neuronal circuits, and the impact of molecular mechanisms on cognitive impairments.</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Molecular Neuroscience<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fnmol.2023.1239315" target="_blank">https://dx.doi.org/10.3389/fnmol.2023.1239315</a></p>2023-06-29T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3389/fnmol.2023.1239315https://figshare.com/articles/journal_contribution/Editorial_Advances_in_understanding_synaptic_function_and_its_dysfunction_in_neurological_disorders/26776519CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/267765192023-06-29T09:00:00Z |
| spellingShingle | Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders Farhan Mohammad (256409) Biomedical and clinical sciences Clinical sciences Neurosciences synaptic plasticity cognition neurological disorder animal models molecular mechanism |
| status_str | publishedVersion |
| title | Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders |
| title_full | Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders |
| title_fullStr | Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders |
| title_full_unstemmed | Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders |
| title_short | Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders |
| title_sort | Editorial: Advances in understanding synaptic function and its dysfunction in neurological disorders |
| topic | Biomedical and clinical sciences Clinical sciences Neurosciences synaptic plasticity cognition neurological disorder animal models molecular mechanism |