Trichosporon asahii fungemia and COVID-19 co-infection: An emerging fungal pathogen; case report and review of the literature
<p dir="ltr">With the evolving COVID-19 pandemic, increasing concerns about invasive fungal infections have been reported particularly with the use of potent immunosuppressant medications to treat the immunological storms in patients with severe COVID-19 illnesses. Trichosporon asahi...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | , , |
| Published: |
2021
|
| Subjects: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1864513547799625728 |
|---|---|
| author | Gawahir A. Ali (14777260) |
| author2 | Ahmed Husain (14777257) Husam Salah (14649992) Wael Goravey (14777254) |
| author2_role | author author author |
| author_facet | Gawahir A. Ali (14777260) Ahmed Husain (14777257) Husam Salah (14649992) Wael Goravey (14777254) |
| author_role | author |
| dc.creator.none.fl_str_mv | Gawahir A. Ali (14777260) Ahmed Husain (14777257) Husam Salah (14649992) Wael Goravey (14777254) |
| dc.date.none.fl_str_mv | 2021-08-03T00:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.idcr.2021.e01244 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Trichosporon_asahii_fungemia_and_COVID-19_co-infection_An_emerging_fungal_pathogen_case_report_and_review_of_the_literature/24420475 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences COVID-19 Trichosporon asahii Fungemia Voriconazole Central venous catheters |
| dc.title.none.fl_str_mv | Trichosporon asahii fungemia and COVID-19 co-infection: An emerging fungal pathogen; case report and review of the literature |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">With the evolving COVID-19 pandemic, increasing concerns about invasive fungal infections have been reported particularly with the use of potent immunosuppressant medications to treat the immunological storms in patients with severe COVID-19 illnesses. Trichosporon asahii (T. asahii) is an emerging highly resistant pathogen with considerable mortality particularly in critically ill patients and immunocompromised individuals. We describe a case of a 58-year-old patient who developed T. asahii fungemia after using immunosuppressant agents for his severe COVID-19 related cytokines release syndrome. Pseudohyphae, arthroconidia, and lateral blastoconidia were seen in the stain, and later confirmed to be T. asahii. Voriconazole successfully treated this multi-drug-resistant fungal infection. The clinical presentation, assessment, and management are reviewed to raise awareness of the circumstances leading to coinfection with this emerging resistant yeast.</p><h2>Other Information</h2><p dir="ltr">Published in: IDCases<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.idcr.2021.e01244" target="_blank">https://dx.doi.org/10.1016/j.idcr.2021.e01244</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_0c59d6a49d7539015f75d652a27ea271 |
| identifier_str_mv | 10.1016/j.idcr.2021.e01244 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/24420475 |
| publishDate | 2021 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Trichosporon asahii fungemia and COVID-19 co-infection: An emerging fungal pathogen; case report and review of the literatureGawahir A. Ali (14777260)Ahmed Husain (14777257)Husam Salah (14649992)Wael Goravey (14777254)Biomedical and clinical sciencesCardiovascular medicine and haematologyClinical sciencesCOVID-19Trichosporon asahiiFungemiaVoriconazoleCentral venous catheters<p dir="ltr">With the evolving COVID-19 pandemic, increasing concerns about invasive fungal infections have been reported particularly with the use of potent immunosuppressant medications to treat the immunological storms in patients with severe COVID-19 illnesses. Trichosporon asahii (T. asahii) is an emerging highly resistant pathogen with considerable mortality particularly in critically ill patients and immunocompromised individuals. We describe a case of a 58-year-old patient who developed T. asahii fungemia after using immunosuppressant agents for his severe COVID-19 related cytokines release syndrome. Pseudohyphae, arthroconidia, and lateral blastoconidia were seen in the stain, and later confirmed to be T. asahii. Voriconazole successfully treated this multi-drug-resistant fungal infection. The clinical presentation, assessment, and management are reviewed to raise awareness of the circumstances leading to coinfection with this emerging resistant yeast.</p><h2>Other Information</h2><p dir="ltr">Published in: IDCases<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.idcr.2021.e01244" target="_blank">https://dx.doi.org/10.1016/j.idcr.2021.e01244</a></p>2021-08-03T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.idcr.2021.e01244https://figshare.com/articles/journal_contribution/Trichosporon_asahii_fungemia_and_COVID-19_co-infection_An_emerging_fungal_pathogen_case_report_and_review_of_the_literature/24420475CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/244204752021-08-03T00:00:00Z |
| spellingShingle | Trichosporon asahii fungemia and COVID-19 co-infection: An emerging fungal pathogen; case report and review of the literature Gawahir A. Ali (14777260) Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences COVID-19 Trichosporon asahii Fungemia Voriconazole Central venous catheters |
| status_str | publishedVersion |
| title | Trichosporon asahii fungemia and COVID-19 co-infection: An emerging fungal pathogen; case report and review of the literature |
| title_full | Trichosporon asahii fungemia and COVID-19 co-infection: An emerging fungal pathogen; case report and review of the literature |
| title_fullStr | Trichosporon asahii fungemia and COVID-19 co-infection: An emerging fungal pathogen; case report and review of the literature |
| title_full_unstemmed | Trichosporon asahii fungemia and COVID-19 co-infection: An emerging fungal pathogen; case report and review of the literature |
| title_short | Trichosporon asahii fungemia and COVID-19 co-infection: An emerging fungal pathogen; case report and review of the literature |
| title_sort | Trichosporon asahii fungemia and COVID-19 co-infection: An emerging fungal pathogen; case report and review of the literature |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences COVID-19 Trichosporon asahii Fungemia Voriconazole Central venous catheters |