FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2

FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2

<p dir="ltr">FBXW7 is a member of the F-box protein family, which functions as the substrate recognition component of the SCF E3 ubiquitin ligase. FBXW7 is a main tumor suppressor due to its ability to control proteasome-mediated degradation of several oncoproteins such as c-Jun, c-M...

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Bibliographic Details
Main Author: Rafael Jiménez-Izquierdo (19482373) (author)
Other Authors: Rosario Morrugares (19482376) (author), Lucía Suanes-Cobos (19482379) (author), Alejandro Correa-Sáez (13027239) (author), Martín Garrido-Rodríguez (19482382) (author), Laura Cerero-Tejero (19482385) (author), Omar M. Khan (17807774) (author), Susana de la Luna (266616) (author), Rocío Sancho (14908566) (author), Marco A. Calzado (7833170) (author)
Published: 2023
Subjects:
Biomedical and clinical sciences
Oncology and carcinogenesis
Pharmacology and pharmaceutical sciences
FBXW7
F-box Proteins
SCF E3 Ubiquitin Ligase
Tumor Suppressor
DYRK2
Phosphorylation
Chemotherapy
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