Helicobacter pylori infection manifesting as Hypereosinophilic syndrome and immune thrombocytopenia complicated by portal vein thrombosis and ischemic colitis

<p dir="ltr"><u>Hypereosinophilic syndromes</u> (HES) are a group of uncommon disorders characterized by persistent <u>eosinophils </u>overproduction which can lead to <u>tissue damage</u> and organs dysfunction secondary to eosinophils tissue infi...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Awni Alshurafa (15468195) (author)
مؤلفون آخرون: Mustafa Sied (21323804) (author), Maab Elkhdier (21323807) (author), Ahmed M. Abdalhadi (20321922) (author), Mohamed A. Yassin (8361183) (author)
منشور في: 2022
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author Awni Alshurafa (15468195)
author2 Mustafa Sied (21323804)
Maab Elkhdier (21323807)
Ahmed M. Abdalhadi (20321922)
Mohamed A. Yassin (8361183)
author2_role author
author
author
author
author_facet Awni Alshurafa (15468195)
Mustafa Sied (21323804)
Maab Elkhdier (21323807)
Ahmed M. Abdalhadi (20321922)
Mohamed A. Yassin (8361183)
author_role author
dc.creator.none.fl_str_mv Awni Alshurafa (15468195)
Mustafa Sied (21323804)
Maab Elkhdier (21323807)
Ahmed M. Abdalhadi (20321922)
Mohamed A. Yassin (8361183)
dc.date.none.fl_str_mv 2022-02-15T09:00:00Z
dc.identifier.none.fl_str_mv 10.1016/j.idcr.2022.e01451
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Helicobacter_pylori_infection_manifesting_as_Hypereosinophilic_syndrome_and_immune_thrombocytopenia_complicated_by_portal_vein_thrombosis_and_ischemic_colitis/29022257
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Cardiovascular medicine and haematology
Immunology
Hypereosinophilic syndrome
Immune thrombocytopenia
H. Pylori
Portal vein thrombosis
dc.title.none.fl_str_mv Helicobacter pylori infection manifesting as Hypereosinophilic syndrome and immune thrombocytopenia complicated by portal vein thrombosis and ischemic colitis
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr"><u>Hypereosinophilic syndromes</u> (HES) are a group of uncommon disorders characterized by persistent <u>eosinophils </u>overproduction which can lead to <u>tissue damage</u> and organs dysfunction secondary to eosinophils tissue infiltration and inflammatory mediators’ release. Causes of secondary HES include <u>parasitic</u><u> infection</u>, some <u>solid tumors</u>, underlying <u>connective tissue disease</u>, <u>allergic conditions</u> and <u>T cell lymphoma</u>. Helicobacter <u>pylori </u>(<i>H. pylori</i>) has been reported only once as a cause of secondary HES in the literature. We report the second case of <i>H. pylori</i> infection in 29-year-old male patient who presents with HES and secondary Immune thrombocytopenic purpura (ITP). This case is different from the first reported case by the presence of HES complication on presentation manifesting as <u>portal vein thrombosis</u>, which was further complicated by <u>ischemic colitis</u>.<i> H, pylori </i><u>eradication therapy</u> alone was successful in a resolution of <u>hypereosinophilia</u> and platelets recovery without the need of corticosteroids or any other treatment.</p><h2>Other Information</h2><p dir="ltr">Published in: IDCases<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.idcr.2022.e01451" target="_blank">https://dx.doi.org/10.1016/j.idcr.2022.e01451</a></p>
eu_rights_str_mv openAccess
id Manara2_0e7e69042a2e892b9867b6c26413ad05
identifier_str_mv 10.1016/j.idcr.2022.e01451
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/29022257
publishDate 2022
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rights_invalid_str_mv CC BY 4.0
spelling Helicobacter pylori infection manifesting as Hypereosinophilic syndrome and immune thrombocytopenia complicated by portal vein thrombosis and ischemic colitisAwni Alshurafa (15468195)Mustafa Sied (21323804)Maab Elkhdier (21323807)Ahmed M. Abdalhadi (20321922)Mohamed A. Yassin (8361183)Biomedical and clinical sciencesCardiovascular medicine and haematologyImmunologyHypereosinophilic syndromeImmune thrombocytopeniaH. PyloriPortal vein thrombosis<p dir="ltr"><u>Hypereosinophilic syndromes</u> (HES) are a group of uncommon disorders characterized by persistent <u>eosinophils </u>overproduction which can lead to <u>tissue damage</u> and organs dysfunction secondary to eosinophils tissue infiltration and inflammatory mediators’ release. Causes of secondary HES include <u>parasitic</u><u> infection</u>, some <u>solid tumors</u>, underlying <u>connective tissue disease</u>, <u>allergic conditions</u> and <u>T cell lymphoma</u>. Helicobacter <u>pylori </u>(<i>H. pylori</i>) has been reported only once as a cause of secondary HES in the literature. We report the second case of <i>H. pylori</i> infection in 29-year-old male patient who presents with HES and secondary Immune thrombocytopenic purpura (ITP). This case is different from the first reported case by the presence of HES complication on presentation manifesting as <u>portal vein thrombosis</u>, which was further complicated by <u>ischemic colitis</u>.<i> H, pylori </i><u>eradication therapy</u> alone was successful in a resolution of <u>hypereosinophilia</u> and platelets recovery without the need of corticosteroids or any other treatment.</p><h2>Other Information</h2><p dir="ltr">Published in: IDCases<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.idcr.2022.e01451" target="_blank">https://dx.doi.org/10.1016/j.idcr.2022.e01451</a></p>2022-02-15T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.idcr.2022.e01451https://figshare.com/articles/journal_contribution/Helicobacter_pylori_infection_manifesting_as_Hypereosinophilic_syndrome_and_immune_thrombocytopenia_complicated_by_portal_vein_thrombosis_and_ischemic_colitis/29022257CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/290222572022-02-15T09:00:00Z
spellingShingle Helicobacter pylori infection manifesting as Hypereosinophilic syndrome and immune thrombocytopenia complicated by portal vein thrombosis and ischemic colitis
Awni Alshurafa (15468195)
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Immunology
Hypereosinophilic syndrome
Immune thrombocytopenia
H. Pylori
Portal vein thrombosis
status_str publishedVersion
title Helicobacter pylori infection manifesting as Hypereosinophilic syndrome and immune thrombocytopenia complicated by portal vein thrombosis and ischemic colitis
title_full Helicobacter pylori infection manifesting as Hypereosinophilic syndrome and immune thrombocytopenia complicated by portal vein thrombosis and ischemic colitis
title_fullStr Helicobacter pylori infection manifesting as Hypereosinophilic syndrome and immune thrombocytopenia complicated by portal vein thrombosis and ischemic colitis
title_full_unstemmed Helicobacter pylori infection manifesting as Hypereosinophilic syndrome and immune thrombocytopenia complicated by portal vein thrombosis and ischemic colitis
title_short Helicobacter pylori infection manifesting as Hypereosinophilic syndrome and immune thrombocytopenia complicated by portal vein thrombosis and ischemic colitis
title_sort Helicobacter pylori infection manifesting as Hypereosinophilic syndrome and immune thrombocytopenia complicated by portal vein thrombosis and ischemic colitis
topic Biomedical and clinical sciences
Cardiovascular medicine and haematology
Immunology
Hypereosinophilic syndrome
Immune thrombocytopenia
H. Pylori
Portal vein thrombosis