Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up
<h2>Background</h2> <p>Long-term durability of weight loss and comorbidity resolution beyond 7 years after laparoscopic sleeve gastrectomy (LSG) among adolescents is completely lacking.</p> <h2>Methods</h2> <p>Retrospective review of adolescents aged ≤ 18 ye...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | |
| منشور في: |
2022
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1864513567431065600 |
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| author | Wahiba Elhag (5245547) |
| author2 | Walid El Ansari (93732) |
| author2_role | author |
| author_facet | Wahiba Elhag (5245547) Walid El Ansari (93732) |
| author_role | author |
| dc.creator.none.fl_str_mv | Wahiba Elhag (5245547) Walid El Ansari (93732) |
| dc.date.none.fl_str_mv | 2022-11-22T21:14:55Z |
| dc.identifier.none.fl_str_mv | 10.1007/s11695-021-05364-3 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Durability_of_Cardiometabolic_Outcomes_Among_Adolescents_After_Sleeve_Gastrectomy_First_Study_with_9-Year_Follow-up/21597624 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Medical biochemistry and metabolomics Nutrition and dietetics Nutrition and Dietetics Endocrinology, Diabetes and Metabolism Surgery |
| dc.title.none.fl_str_mv | Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h2>Background</h2> <p>Long-term durability of weight loss and comorbidity resolution beyond 7 years after laparoscopic sleeve gastrectomy (LSG) among adolescents is completely lacking.</p> <h2>Methods</h2> <p>Retrospective review of adolescents aged ≤ 18 years who underwent primary LSG at our institution between 2011 and 2015 (N = 146). We assessed anthropometric and cardiometabolic outcomes at 1, 3, 5, 7, and 9 years.</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). Remission rates were triglycerides, 100% (11/11) at 5 years, and 100% (1/1) at 9 years; high density lipoprotein, 89.4% (17/19) at 5 years, and 100% (3/3) at 7 years; low density lipoprotein, 71.4% (11/14) and 100% (3/3) at 5 and 7 years; total cholesterol, 70% (7/10) at 5 years, and 100% (2/2) at 9 years; uric acid, 100% (3/3) at 5 years. Remission of liver enzymes was 84.6–100% (22/26–2/2) at 5–9 years. Prediabetes remission was 87.5% (14/16 and 7/8) at 5 and 7 years and 100% (3/3) at year 9. Type 2 diabetes complete remission was 50% (3/6, 1/2) at years 5 and 7, with all cases resolved at 9 years. The only case of hypertension completely resolved.</p> <h2>Conclusions</h2> <p>LSG achieved substantial weight loss and remission of cardiometabolic risk factors that were sustained on the long term. This is the first study among adolescents to assess such outcomes beyond 7 years.</p><h2>Other Information</h2> <p> Published in: Obesity Surgery<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s11695-021-05364-3" target="_blank">http://dx.doi.org/10.1007/s11695-021-05364-3</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_0f18e13657c811b99f8b04d2c05fe526 |
| identifier_str_mv | 10.1007/s11695-021-05364-3 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/21597624 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-upWahiba Elhag (5245547)Walid El Ansari (93732)Medical biochemistry and metabolomicsNutrition and dieteticsNutrition and DieteticsEndocrinology, Diabetes and MetabolismSurgery<h2>Background</h2> <p>Long-term durability of weight loss and comorbidity resolution beyond 7 years after laparoscopic sleeve gastrectomy (LSG) among adolescents is completely lacking.</p> <h2>Methods</h2> <p>Retrospective review of adolescents aged ≤ 18 years who underwent primary LSG at our institution between 2011 and 2015 (N = 146). We assessed anthropometric and cardiometabolic outcomes at 1, 3, 5, 7, and 9 years.</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). Remission rates were triglycerides, 100% (11/11) at 5 years, and 100% (1/1) at 9 years; high density lipoprotein, 89.4% (17/19) at 5 years, and 100% (3/3) at 7 years; low density lipoprotein, 71.4% (11/14) and 100% (3/3) at 5 and 7 years; total cholesterol, 70% (7/10) at 5 years, and 100% (2/2) at 9 years; uric acid, 100% (3/3) at 5 years. Remission of liver enzymes was 84.6–100% (22/26–2/2) at 5–9 years. Prediabetes remission was 87.5% (14/16 and 7/8) at 5 and 7 years and 100% (3/3) at year 9. Type 2 diabetes complete remission was 50% (3/6, 1/2) at years 5 and 7, with all cases resolved at 9 years. The only case of hypertension completely resolved.</p> <h2>Conclusions</h2> <p>LSG achieved substantial weight loss and remission of cardiometabolic risk factors that were sustained on the long term. This is the first study among adolescents to assess such outcomes beyond 7 years.</p><h2>Other Information</h2> <p> Published in: Obesity Surgery<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s11695-021-05364-3" target="_blank">http://dx.doi.org/10.1007/s11695-021-05364-3</a></p>2022-11-22T21:14:55ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s11695-021-05364-3https://figshare.com/articles/journal_contribution/Durability_of_Cardiometabolic_Outcomes_Among_Adolescents_After_Sleeve_Gastrectomy_First_Study_with_9-Year_Follow-up/21597624CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/215976242022-11-22T21:14:55Z |
| spellingShingle | Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up Wahiba Elhag (5245547) Medical biochemistry and metabolomics Nutrition and dietetics Nutrition and Dietetics Endocrinology, Diabetes and Metabolism Surgery |
| status_str | publishedVersion |
| title | Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up |
| title_full | Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up |
| title_fullStr | Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up |
| title_full_unstemmed | Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up |
| title_short | Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up |
| title_sort | Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up |
| topic | Medical biochemistry and metabolomics Nutrition and dietetics Nutrition and Dietetics Endocrinology, Diabetes and Metabolism Surgery |