Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health
<p dir="ltr">Obesity is a leading cause of morbidity and mortality globally. While the prevalence of obesity has been increasing, the incidence of its related complications including dyslipidemia and cardiovascular disease (CVD) has also been rising. Recent research has focused on mo...
محفوظ في:
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| مؤلفون آخرون: | , , , |
| منشور في: |
2024
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| الموضوعات: | |
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| _version_ | 1864513542159335424 |
|---|---|
| author | Rawan Diab (16941484) |
| author2 | Lina Dimachkie (21842264) Omar Zein (21842267) Ali Dakroub (21842270) Ali H. Eid (5461829) |
| author2_role | author author author author |
| author_facet | Rawan Diab (16941484) Lina Dimachkie (21842264) Omar Zein (21842267) Ali Dakroub (21842270) Ali H. Eid (5461829) |
| author_role | author |
| dc.creator.none.fl_str_mv | Rawan Diab (16941484) Lina Dimachkie (21842264) Omar Zein (21842267) Ali Dakroub (21842270) Ali H. Eid (5461829) |
| dc.date.none.fl_str_mv | 2024-06-07T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1007/s12013-024-01314-9 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Intermittent_Fasting_Regulates_Metabolic_Homeostasis_and_Improves_Cardiovascular_Health/29715758 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Medical biochemistry and metabolomics Nutrition and dietetics Health sciences Public health Cardiovascular disease Metabolic disease Caloric restriction Dyslipidemia Adipose tissue |
| dc.title.none.fl_str_mv | Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Obesity is a leading cause of morbidity and mortality globally. While the prevalence of obesity has been increasing, the incidence of its related complications including dyslipidemia and cardiovascular disease (CVD) has also been rising. Recent research has focused on modalities aimed at reducing obesity. Several modalities have been suggested including behavioral and dietary changes, medications, and bariatric surgery. These modalities differ in their effectiveness and invasiveness, with dietary changes gaining more interest due to their minimal risks compared to other modalities. Specifically, intermittent fasting (IF) has been gaining interest in the past decade. IF is characterized by cycles of alternating fasting and eating windows, with several different forms practiced. IF has been shown to reduce weight and alleviate obesity-related complications. Our review of clinical and experimental studies explores the effects of IF on the lipid profile, white adipose tissue (WAT) dynamics, and the gut microbiome. Notably, IF corrects dyslipidemia, reduces WAT accumulation, and decreases inflammation, which reduces CVD and obesity. This comprehensive analysis details the protective metabolic role of IF, advocating for its integration into public health practices.</p><h2>Other Information</h2><p dir="ltr">Published in: Cell Biochemistry and Biophysics<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s12013-024-01314-9" target="_blank">https://dx.doi.org/10.1007/s12013-024-01314-9</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_137f37db7295b0b17a33425c4c06d07b |
| identifier_str_mv | 10.1007/s12013-024-01314-9 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29715758 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular HealthRawan Diab (16941484)Lina Dimachkie (21842264)Omar Zein (21842267)Ali Dakroub (21842270)Ali H. Eid (5461829)Biomedical and clinical sciencesCardiovascular medicine and haematologyMedical biochemistry and metabolomicsNutrition and dieteticsHealth sciencesPublic healthCardiovascular diseaseMetabolic diseaseCaloric restrictionDyslipidemiaAdipose tissue<p dir="ltr">Obesity is a leading cause of morbidity and mortality globally. While the prevalence of obesity has been increasing, the incidence of its related complications including dyslipidemia and cardiovascular disease (CVD) has also been rising. Recent research has focused on modalities aimed at reducing obesity. Several modalities have been suggested including behavioral and dietary changes, medications, and bariatric surgery. These modalities differ in their effectiveness and invasiveness, with dietary changes gaining more interest due to their minimal risks compared to other modalities. Specifically, intermittent fasting (IF) has been gaining interest in the past decade. IF is characterized by cycles of alternating fasting and eating windows, with several different forms practiced. IF has been shown to reduce weight and alleviate obesity-related complications. Our review of clinical and experimental studies explores the effects of IF on the lipid profile, white adipose tissue (WAT) dynamics, and the gut microbiome. Notably, IF corrects dyslipidemia, reduces WAT accumulation, and decreases inflammation, which reduces CVD and obesity. This comprehensive analysis details the protective metabolic role of IF, advocating for its integration into public health practices.</p><h2>Other Information</h2><p dir="ltr">Published in: Cell Biochemistry and Biophysics<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s12013-024-01314-9" target="_blank">https://dx.doi.org/10.1007/s12013-024-01314-9</a></p>2024-06-07T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s12013-024-01314-9https://figshare.com/articles/journal_contribution/Intermittent_Fasting_Regulates_Metabolic_Homeostasis_and_Improves_Cardiovascular_Health/29715758CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/297157582024-06-07T03:00:00Z |
| spellingShingle | Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health Rawan Diab (16941484) Biomedical and clinical sciences Cardiovascular medicine and haematology Medical biochemistry and metabolomics Nutrition and dietetics Health sciences Public health Cardiovascular disease Metabolic disease Caloric restriction Dyslipidemia Adipose tissue |
| status_str | publishedVersion |
| title | Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health |
| title_full | Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health |
| title_fullStr | Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health |
| title_full_unstemmed | Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health |
| title_short | Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health |
| title_sort | Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Medical biochemistry and metabolomics Nutrition and dietetics Health sciences Public health Cardiovascular disease Metabolic disease Caloric restriction Dyslipidemia Adipose tissue |