Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutions
<p dir="ltr">The therapeutic properties of medicinal plants have been harnessed to facilitate wound healing, and conventional techniques for their application in this regard have been devised. Electrospun nanofibrous scaffolds have recently shown great potential as materials for tiss...
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2025
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| _version_ | 1864513534120951808 |
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| author | Hemalatha Parangusan (6556133) |
| author2 | K. Karuppasamy (6087320) Jolly Bhadra (14147823) |
| author2_role | author author |
| author_facet | Hemalatha Parangusan (6556133) K. Karuppasamy (6087320) Jolly Bhadra (14147823) |
| author_role | author |
| dc.creator.none.fl_str_mv | Hemalatha Parangusan (6556133) K. Karuppasamy (6087320) Jolly Bhadra (14147823) |
| dc.date.none.fl_str_mv | 2025-05-02T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1007/s10965-025-04373-5 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Fenugreek-enriched_electrospun_PLA_scaffold_revolutionizing_tissue_engineering_solutions/30454301 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Engineering Materials engineering Nanotechnology Poly (lactic acid) Fenugreek Electrospinning Scaffolds Wound healing |
| dc.title.none.fl_str_mv | Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutions |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">The therapeutic properties of medicinal plants have been harnessed to facilitate wound healing, and conventional techniques for their application in this regard have been devised. Electrospun nanofibrous scaffolds have recently shown great potential as materials for tissue engineering, specifically tissue regeneration. Utilizing medicinal plant components in nanofibers for biomedical and wound healing purposes holds promise for improving performance and achieving a synergistic outcome. The scaffolds that were created underwent analysis using X-ray diffraction, Fourier transform, mechanical testing, swelling measurement, contact angle measurement, and weight loss assessment. The study also examined the compatibility of the cells with the scaffolds and assessed their wound-healing capacity in a laboratory setting. The scanning electron microscopy (SEM) images of the PLA and PLA/fenugreek composite scaffolds demonstrate the presence of uniform, sleek, and flawless nanofibers. The investigation yielded significant evidence regarding the in vitro wound healing and cell viability of 3 T3 fibroblast cells on the produced scaffolds. The findings demonstrated that PLA scaffolds with fenugreek exhibit promising potential as substitutes for tissue engineering purposes.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Polymer Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10965-025-04373-5" target="_blank">https://dx.doi.org/10.1007/s10965-025-04373-5</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_18a48c80d1bb1e4c8468eddf9fcf75bc |
| identifier_str_mv | 10.1007/s10965-025-04373-5 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30454301 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutionsHemalatha Parangusan (6556133)K. Karuppasamy (6087320)Jolly Bhadra (14147823)EngineeringMaterials engineeringNanotechnologyPoly (lactic acid)FenugreekElectrospinningScaffoldsWound healing<p dir="ltr">The therapeutic properties of medicinal plants have been harnessed to facilitate wound healing, and conventional techniques for their application in this regard have been devised. Electrospun nanofibrous scaffolds have recently shown great potential as materials for tissue engineering, specifically tissue regeneration. Utilizing medicinal plant components in nanofibers for biomedical and wound healing purposes holds promise for improving performance and achieving a synergistic outcome. The scaffolds that were created underwent analysis using X-ray diffraction, Fourier transform, mechanical testing, swelling measurement, contact angle measurement, and weight loss assessment. The study also examined the compatibility of the cells with the scaffolds and assessed their wound-healing capacity in a laboratory setting. The scanning electron microscopy (SEM) images of the PLA and PLA/fenugreek composite scaffolds demonstrate the presence of uniform, sleek, and flawless nanofibers. The investigation yielded significant evidence regarding the in vitro wound healing and cell viability of 3 T3 fibroblast cells on the produced scaffolds. The findings demonstrated that PLA scaffolds with fenugreek exhibit promising potential as substitutes for tissue engineering purposes.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Polymer Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10965-025-04373-5" target="_blank">https://dx.doi.org/10.1007/s10965-025-04373-5</a></p>2025-05-02T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s10965-025-04373-5https://figshare.com/articles/journal_contribution/Fenugreek-enriched_electrospun_PLA_scaffold_revolutionizing_tissue_engineering_solutions/30454301CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/304543012025-05-02T03:00:00Z |
| spellingShingle | Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutions Hemalatha Parangusan (6556133) Engineering Materials engineering Nanotechnology Poly (lactic acid) Fenugreek Electrospinning Scaffolds Wound healing |
| status_str | publishedVersion |
| title | Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutions |
| title_full | Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutions |
| title_fullStr | Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutions |
| title_full_unstemmed | Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutions |
| title_short | Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutions |
| title_sort | Fenugreek-enriched electrospun PLA scaffold: revolutionizing tissue engineering solutions |
| topic | Engineering Materials engineering Nanotechnology Poly (lactic acid) Fenugreek Electrospinning Scaffolds Wound healing |