Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells

Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells

<p>Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by triggering apoptotic cell death. Apoptosis induced by NSP-B is triggere...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Shilpa Kuttikrishnan (3520079) (author)
مؤلفون آخرون:	Ajaz A. Bhat (12984701) (author), Jericha M. Mateo (17563293) (author), Fareed Ahmad (134672) (author), Feras Q. Alali (2691907) (author), Tamam El-Elimat (694398) (author), Nicholas H. Oberlies (326437) (author), Cedric J. Pearce (1364220) (author), Shahab Uddin (154400) (author)
منشور في:	2022
الموضوعات:	Biological sciences Biochemistry and cell biology Biomedical and clinical sciences Cardiovascular medicine and haematology Oncology and carcinogenesis Natural products Meroterpenoids Fungal secondary metabolites Neosetophomone B Apoptosis Leukemia
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

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