Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review

<p dir="ltr">Bacillus amyloliquefaciens, a Gram-positive bacterium, has emerged as a versatile microorganism with significant applications in various fields, including industry, medicine, and agriculture. This comprehensive review aims to provide an in-depth understanding of the char...

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Main Author: Imen Zalila-Kolsi (19368502) (author)
Other Authors: Afif Ben-Mahmoud (13913550) (author), Ray Al-Barazie (19368505) (author)
Published: 2023
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author Imen Zalila-Kolsi (19368502)
author2 Afif Ben-Mahmoud (13913550)
Ray Al-Barazie (19368505)
author2_role author
author
author_facet Imen Zalila-Kolsi (19368502)
Afif Ben-Mahmoud (13913550)
Ray Al-Barazie (19368505)
author_role author
dc.creator.none.fl_str_mv Imen Zalila-Kolsi (19368502)
Afif Ben-Mahmoud (13913550)
Ray Al-Barazie (19368505)
dc.date.none.fl_str_mv 2023-08-31T09:00:00Z
dc.identifier.none.fl_str_mv 10.3390/microorganisms11092215
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Bacillus_amyloliquefaciens_Harnessing_Its_Potential_for_Industrial_Medical_and_Agricultural_Applications_A_Comprehensive_Review/26539456
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biological sciences
Microbiology
Biomedical and clinical sciences
Clinical sciences
Bacillus amyloliquefaciens
industrial applications
medical applications
agricultural applications
metabolic engineering
dc.title.none.fl_str_mv Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">Bacillus amyloliquefaciens, a Gram-positive bacterium, has emerged as a versatile microorganism with significant applications in various fields, including industry, medicine, and agriculture. This comprehensive review aims to provide an in-depth understanding of the characteristics, genetic tools, and metabolic capabilities of B. amyloliquefaciens, while highlighting its potential as a chassis cell for synthetic biology, metabolic engineering, and protein expression. We discuss the bacterium’s role in the production of chemicals, enzymes, and other industrial bioproducts, as well as its applications in medicine, such as combating infectious diseases and promoting gut health. In agriculture, B. amyloliquefaciens has demonstrated potential as a biofertilizer, biocontrol agent, and stress tolerance enhancer for various crops. Despite its numerous promising applications, B. amyloliquefaciens remains less studied than its Gram-negative counterpart, Escherichia coli. This review emphasizes the need for further research and development of advanced engineering techniques and genetic editing technologies tailored for B. amyloliquefaciens, ultimately unlocking its full potential in scientific and industrial contexts.</p><h2>Other Information</h2><p dir="ltr">Published in: Microorganisms<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/microorganisms11092215" target="_blank">https://dx.doi.org/10.3390/microorganisms11092215</a></p>
eu_rights_str_mv openAccess
id Manara2_1a17232b686645d4fe9624b6723b5f6e
identifier_str_mv 10.3390/microorganisms11092215
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/26539456
publishDate 2023
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rights_invalid_str_mv CC BY 4.0
spelling Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive ReviewImen Zalila-Kolsi (19368502)Afif Ben-Mahmoud (13913550)Ray Al-Barazie (19368505)Biological sciencesMicrobiologyBiomedical and clinical sciencesClinical sciencesBacillus amyloliquefaciensindustrial applicationsmedical applicationsagricultural applicationsmetabolic engineering<p dir="ltr">Bacillus amyloliquefaciens, a Gram-positive bacterium, has emerged as a versatile microorganism with significant applications in various fields, including industry, medicine, and agriculture. This comprehensive review aims to provide an in-depth understanding of the characteristics, genetic tools, and metabolic capabilities of B. amyloliquefaciens, while highlighting its potential as a chassis cell for synthetic biology, metabolic engineering, and protein expression. We discuss the bacterium’s role in the production of chemicals, enzymes, and other industrial bioproducts, as well as its applications in medicine, such as combating infectious diseases and promoting gut health. In agriculture, B. amyloliquefaciens has demonstrated potential as a biofertilizer, biocontrol agent, and stress tolerance enhancer for various crops. Despite its numerous promising applications, B. amyloliquefaciens remains less studied than its Gram-negative counterpart, Escherichia coli. This review emphasizes the need for further research and development of advanced engineering techniques and genetic editing technologies tailored for B. amyloliquefaciens, ultimately unlocking its full potential in scientific and industrial contexts.</p><h2>Other Information</h2><p dir="ltr">Published in: Microorganisms<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/microorganisms11092215" target="_blank">https://dx.doi.org/10.3390/microorganisms11092215</a></p>2023-08-31T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3390/microorganisms11092215https://figshare.com/articles/journal_contribution/Bacillus_amyloliquefaciens_Harnessing_Its_Potential_for_Industrial_Medical_and_Agricultural_Applications_A_Comprehensive_Review/26539456CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/265394562023-08-31T09:00:00Z
spellingShingle Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review
Imen Zalila-Kolsi (19368502)
Biological sciences
Microbiology
Biomedical and clinical sciences
Clinical sciences
Bacillus amyloliquefaciens
industrial applications
medical applications
agricultural applications
metabolic engineering
status_str publishedVersion
title Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review
title_full Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review
title_fullStr Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review
title_full_unstemmed Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review
title_short Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review
title_sort Bacillus amyloliquefaciens: Harnessing Its Potential for Industrial, Medical, and Agricultural Applications—A Comprehensive Review
topic Biological sciences
Microbiology
Biomedical and clinical sciences
Clinical sciences
Bacillus amyloliquefaciens
industrial applications
medical applications
agricultural applications
metabolic engineering